Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.33 |
| ▸ | CD38 | P28907 | 3/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.32 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.32 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4064582 | 0.74 | GLA (0.52) | PKM | |
| SCHEMBL4065421 | 0.70 | HPGD (0.53) | HSD17B10PKMNAMPT | |
| SCHEMBL6630344 | 0.68 | CCR4 (0.37) | SLC40A1SLC22A12ERAP1 | |
| SCHEMBL3191542 | 0.61 | ALDH1A1 (0.41) | PKMERAP1NAMPT | |
| SCHEMBL2776699 | 0.61 | PTGES2 (0.53) | SLC22A12PKMPTGES2 | |
| SCHEMBL30586543 | 0.61 | SLC22A12 (0.42) | SLC22A12HSD17B10PKMHSD11B1PTGES2 | |
| SCHEMBL30586498 | 0.61 | PTGES2 (0.53) | SLC22A12PKMPTGES2 | |
| SCHEMBL1501184 | 0.61 | SLC22A12 (0.42) | SLC22A12HSD17B10PKMHSD11B1PTGES2 | |
| SCHEMBL3197747 | 0.61 | SLC22A12 (0.42) | SLC22A12PKMHSD11B1PTGES2STIM1 | |
| SCHEMBL8025930 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322649-B1 | PROCESS FOR THE PREPARATION OF 2-ALKOXY-6-TRIFLUOROMETHYL-N-([1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-2-YL)BENZENESULFONAMIDES | DOW AGROSCIENCES LLC (US) | 2004-05-19 | — | — | EP | claimed |
| EP-1322649-A2 | PROCESS FOR THE PREPARATION OF 2-ALKOXY-6-TRIFLUOROMETHYL-N-([1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-2-YL)BENZENESULFONAMIDES | Dow AgroSciences LLC (US) | 2003-07-02 | — | — | EP | claimed |
| US-6433169-B1 | FORM THE CORRESPONDING 2-FLUORIDE COMPOUND WITH AN ALCOHOL;ETHERIFICATION | DOW AGROSCIENCES LLC | 2002-08-13 | — | — | US | claimed |
| WO-2002026742-A2 | PROCESS FOR THE PREPARATION OF 2-ALKOXY-6-TRIFLUOROMETHYL-N-([1,2,4]TRIAZOLO[1,5-c]PYRIMIDIN-2-YL)BENZENESULFONAMIDES | DOW AGROSCIENCES LLC (US) | 2002-04-04 | — | — | WO | claimed |
| US-20020037811-A1 | Process for the preparation of 2-alkoxy-6-trifluoromethyl-N-([1,2,4]triazolo[1,5-c]pyrimidin-2-yl)benzenesulfonamides | DOW AGROSCIENCES LLC | 2002-03-28 | — | — | US | claimed |
| EP-1322649-B1 | PROCESS FOR THE PREPARATION OF 2-ALKOXY-6-TRIFLUOROMETHYL-N-([1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-2-YL)BENZENESULFONAMIDES | DOW AGROSCIENCES LLC (US) | 2004-05-19 | — | — | EP | disclosed |
| EP-1322649-A2 | PROCESS FOR THE PREPARATION OF 2-ALKOXY-6-TRIFLUOROMETHYL-N-([1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-2-YL)BENZENESULFONAMIDES | Dow AgroSciences LLC (US) | 2003-07-02 | — | — | EP | disclosed |
| US-6433169-B1 | FORM THE CORRESPONDING 2-FLUORIDE COMPOUND WITH AN ALCOHOL;ETHERIFICATION | DOW AGROSCIENCES LLC | 2002-08-13 | — | — | US | disclosed |
| WO-2002026742-A2 | PROCESS FOR THE PREPARATION OF 2-ALKOXY-6-TRIFLUOROMETHYL-N-([1,2,4]TRIAZOLO[1,5-c]PYRIMIDIN-2-YL)BENZENESULFONAMIDES | DOW AGROSCIENCES LLC (US) | 2002-04-04 | — | — | WO | disclosed |
| US-20020037811-A1 | Process for the preparation of 2-alkoxy-6-trifluoromethyl-N-([1,2,4]triazolo[1,5-c]pyrimidin-2-yl)benzenesulfonamides | DOW AGROSCIENCES LLC | 2002-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020037811-A1 | Process for the preparation of 2-alkoxy-6-trifluoromethyl-N-([1,2,4]triazolo[1,5-c]pyrimidin-2-yl)benzenesulfonamides | ALK, AZI2, PNPO | SLC40A1 4264/4885SLC22A12 4528/4885GPBAR1 4594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.