⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3577575 | 0.82 | — | — | |
| SCHEMBL642268 | 0.82 | — | — | |
| SCHEMBL302 | 0.82 | — | — | |
| SCHEMBL72657 | 0.82 | — | — | |
| Methane SCHEMBL1818230 | 0.76 | — | — | |
| Charcoal, Activated SCHEMBL2479918 | 0.76 | — | — | |
| SCHEMBL10394282 | 0.76 | — | — | |
| SCHEMBL7126192 | 0.76 | — | — | |
| Ammonia Solution, Strong SCHEMBL15540045 | 0.76 | — | — | |
| Phosphine SCHEMBL10394278 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1394162-A1 | Intermediates of azole antifungal agents and processes for the preparation thereof | Eisai Co., Ltd. (JP) | 2004-03-03 | — | — | EP | disclosed |
| EP-1394142-A1 | Carboxylic acid intermediates of antifungal agents and processes for the preparation thereof | Eisai Co., Ltd. (JP) | 2004-03-03 | — | — | EP | disclosed |
| EP-1231210-A2 | Azole antifungal agents, processes for the preparation thereof, and intermediates | Eisai Co., Ltd. (JP) | 2002-08-14 | — | — | EP | disclosed |
| CN-1054129-C | Process for the preparation of 3-arylbenzofuranone | CIBA SC HOLDING AG (CH) | 2000-07-05 | — | — | CN | disclosed |
| CN-1049434-C | Aromatic amidine derivatives and pharmaceutically acceptable salts thereof | DAIICHI SEIYAKU CO (JP) | 2000-02-16 | — | — | CN | disclosed |
| US-5792781-A | EFFECTIVE AGAINST DERMATOMYCOSIS/VISCEROMYCOSIS CAUSED BY FUNGI, I.E., CANDIDA ALBICANS | EISAI CO., LTD. (JP) | 1998-08-11 | — | — | US | disclosed |
| US-5789429-A | FUNGICIDE | EISAI CO., LTD. (JP) | 1998-08-04 | — | — | US | disclosed |
| US-5648372-A | TRIAZOLES | EISAI CO., LTD. (JP) | 1997-07-15 | — | — | US | disclosed |
| CN-1111627-A | Process for the preparation of 3-arylbenzofuranone | CIBA GEIGY AG (CH) | 1995-11-15 | — | — | CN | disclosed |
| EP-0667346-A2 | Azole antifungal agents, process for the preparation there of and intermediates | Eisai Co., Ltd. (JP) | 1995-08-16 | — | — | EP | disclosed |