Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4594734 | 0.90 | CYP1A2 (0.41) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6628296 | 0.88 | TSHR (0.42) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6632059 | 0.88 | GAA (0.43) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6631443 | 0.81 | TSHR (0.43) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4595161 | 0.80 | CYP1A2 (0.40) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6632193 | 0.78 | RIPK1 (0.50) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4594031 | 0.78 | CYP1A2 (0.40) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4595876 | 0.78 | GAA (0.40) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6632829 | 0.75 | GAA (0.46) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4595157 | 0.74 | TSHR (0.41) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417209-A1 | HIGH BOILING INHIBITORS FOR DISTILLABLE, POLYMERIZABLE MONOMERS | Crompton Corporation (US) | 2004-05-12 | — | — | EP | claimed |
| WO-2003014130-A1 | HIGH BOILING INHIBITORS FOR DISTILLABLE, POLYMERIZABLE MONOMERS | CROMPTON CORPORATION (US) | 2003-02-20 | — | — | WO | claimed |
| EP-1417209-A1 | HIGH BOILING INHIBITORS FOR DISTILLABLE, POLYMERIZABLE MONOMERS | Crompton Corporation (US) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003014130-A1 | HIGH BOILING INHIBITORS FOR DISTILLABLE, POLYMERIZABLE MONOMERS | CROMPTON CORPORATION (US) | 2003-02-20 | — | — | WO | disclosed |