Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6635030 | 1.00 | MAOB (0.44) | MAOBNR4A2HPGDLMNAKMT2A | |
| SCHEMBL1533101 | 0.84 | NR4A2 (0.46) | MAOBNR4A2HPGDLMNAKMT2A | |
| SCHEMBL2219112 | 0.83 | MAOB (0.44) | MAOBHPGDLMNAKMT2AIDO1 | |
| SCHEMBL12437263 | 0.83 | MAOB (0.44) | MAOBHPGDLMNAKMT2AIDO1 | |
| SCHEMBL5169494 | 0.82 | ALDH1A1 (0.53) | MAOBHPGDLMNAKMT2AHTT | |
| SCHEMBL839677 | 0.82 | ALDH1A1 (0.53) | MAOBHPGDLMNAKMT2AHTT | |
| SCHEMBL5168366 | 0.82 | ALDH1A1 (0.53) | MAOBHPGDLMNAKMT2AHTT | |
| SCHEMBL19896817 | 0.81 | HTT (0.49) | MAOBIDO1AGXTKLK7HTT | |
| SCHEMBL28656889 | 0.81 | ALDH1A1 (0.52) | MAOBHPGDLMNAKMT2AHTT | |
| SCHEMBL1968068 | 0.80 | PPARG (0.47) | HPGDLMNAIDO1AGXTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015433-B1 | SUBSTITUTED 1,2,3,4,5,6-HEXAHYDRO-2,6-METHANO-3-BENZAZOCINE-10-OLES, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-05-26 | — | — | EP | disclosed |
| EP-1015433-A1 | SUBSTITUTED 1,2,3,4,5,6-HEXAHYDRO-2,6-METHANO-3-BENZAZOCINE-10-OLES, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim Pharma KG (DE) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999014199-A1 | SUBSTITUTED 1,2,3,4,5,6-HEXAHYDRO-2,6-METHANO-3-BENZAZOCINE-10-OLES, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-03-25 | — | — | WO | disclosed |