Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PLK1 | P53350 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1563655 | 1.00 | KMT2A (0.56) | KMT2ARAB9AMEN1NPC1POLB | |
| SCHEMBL1563654 | 1.00 | KMT2A (0.56) | KMT2ARAB9AMEN1NPC1POLB | |
| SCHEMBL5705734 | 0.87 | SMN1; SMN2 (0.54) | KMT2ARAB9AMEN1NPC1POLB | |
| SCHEMBL29586502 | 0.87 | SMN1; SMN2 (0.54) | KMT2ARAB9AMEN1NPC1POLB | |
| SCHEMBL2276912 | 0.87 | SMN1; SMN2 (0.54) | KMT2ARAB9AMEN1NPC1POLB | |
| SCHEMBL2276914 | 0.87 | SMN1; SMN2 (0.54) | KMT2ARAB9AMEN1NPC1POLB | |
| SCHEMBL1563022 | 0.85 | KMT2A (0.60) | KMT2ARAB9AMEN1NPC1POLB | |
| SCHEMBL6636696 | 0.85 | KMT2A (0.60) | KMT2ARAB9AMEN1NPC1POLB | |
| SCHEMBL1563020 | 0.85 | KMT2A (0.60) | KMT2ARAB9AMEN1NPC1POLB | |
| SCHEMBL5705557 | 0.82 | GAA (0.68) | KMT2ARAB9AMEN1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0909788-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | BRIDGESTONE CORP (JP) | 2004-12-01 | — | — | EP | disclosed |
| EP-1420044-A2 | Rubber composition and pneumatic tire | Bridgestone Corporation (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6380288-B1 | LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS | BRIDGESTONE CORPORATION | 2002-04-30 | — | — | US | disclosed |
| EP-0909788-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | Bridgestone Corporation (JP) | 1999-04-21 | — | — | EP | disclosed |