SCHEMBL6634814

SCHEMBL6634814

O=S(=O)(O)c1ccc(S(=O)(=O)O)c2c(O)[c]ccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AURKA O14965 1/20 0.44
AURKB Q96GD4 1/20 0.44
COMT P21964 1/20 0.37
TTR P02766 2/20 0.34
CYP1A2 P05177 2/20 0.33
ATIC P31939 1/20 0.33
SNCA P37840 2/20 0.33
CHAT P28329 1/20 0.33
CTRB1 P17538 1/20 0.33
TNNI3 P19429 1/20 0.33
TNNT2 P45379 1/20 0.33
TNNC1 P63316 1/20 0.33
HKDC1 Q2TB90 1/20 0.33
ALDH1A1 P00352 1/20 0.32
ALOX15 P16050 1/20 0.32
HIF1A Q16665 1/20 0.32
HSD17B10 Q99714 1/20 0.32
FABP4 P15090 1/20 0.32
CCNA2 P20248 1/20 0.32
CDK2 P24941 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1413138 0.78 AURKA (0.39) AURKAAURKBTTRCYP1A2ALDH1A1
SCHEMBL7065517 0.78 CYP1A2 (0.47) AURKAAURKBTTRCYP1A2SNCA
SCHEMBL1413154 0.78 TTR (0.34) AURKAAURKBCOMTTTRCYP1A2
SCHEMBL5031748 0.76 TTR (0.53) AURKAAURKBCOMTTTRCYP1A2
SCHEMBL6636066 0.76 COMT (0.37) AURKAAURKBCOMTTTRCYP1A2
SCHEMBL6632032 0.75 AURKA (0.45) AURKAAURKBCOMTTTRCYP1A2
SCHEMBL6633176 0.75 TTR (0.50) AURKAAURKBTTRCYP1A2ATIC
SCHEMBL7894720 0.71 AURKB (0.38) AURKAAURKBCOMTTTRCYP1A2
SCHEMBL6632503 0.70 NT5E (0.33) TTRCYP1A2ATICTNNI3TNNT2
SCHEMBL9621075 0.70 AURKA (0.42) AURKAAURKBCOMTTTRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040231558-A1 Has a clear hue, high light fastness and high moisture resistance MITSUI CHEMICALS, INC. (JP) 2004-11-25 US disclosed
EP-1441013-A1 WATERCOLOR INK Mitsui Chemicals, Inc. (JP) 2004-07-28 EP disclosed