SCHEMBL6636066

SCHEMBL6636066

O=S(=O)(O)c1cc[c]c(O)c1O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
COMT P21964 1/20 0.37
TTR P02766 1/20 0.34
CYP1A2 P05177 2/20 0.33
LMNA P02545 2/20 0.33
PGAM1 P18669 1/20 0.33
AURKA O14965 1/20 0.33
AURKB Q96GD4 1/20 0.33
CTRB1 P17538 1/20 0.33
HSD17B10 Q99714 3/20 0.32
ALDH1A1 P00352 2/20 0.32
HIF1A Q16665 2/20 0.32
ALOX15 P16050 1/20 0.32
CASP1 P29466 1/20 0.32
CASP7 P55210 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NQO1 P15559 1/20 0.31
MPL P40238 1/20 0.30
HPGD P15428 1/20 0.30
RAPGEF4 Q8WZA2 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1413154 0.80 TTR (0.34) COMTTTRCYP1A2AURKAAURKB
SCHEMBL7574819 0.79 CYP1A2 (0.39) COMTTTRCYP1A2AURKAAURKB
SCHEMBL6634814 0.76 AURKA (0.44) COMTTTRCYP1A2AURKAAURKB
SCHEMBL6632839 0.76 ALDH1A1 (0.36) HSD17B10ALDH1A1CASP1CASP7TDP1
SCHEMBL5031748 0.75 TTR (0.53) COMTTTRCYP1A2AURKAAURKB
SCHEMBL176809 0.74 TTR (0.38) COMTTTRCYP1A2LMNAPGAM1
SCHEMBL22471788 0.74 NT5E (0.36) CYP1A2LMNAHSD17B10ALDH1A1HIF1A
SCHEMBL5683924 0.73 PGAM1 (0.45) COMTTTRCYP1A2LMNAPGAM1
SCHEMBL6632503 0.72 NT5E (0.33) TTRCYP1A2HSD17B10ALDH1A1HIF1A
SCHEMBL7044667 0.71 ALDH1A1 (0.39) CYP1A2LMNAHSD17B10ALDH1A1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040231558-A1 Has a clear hue, high light fastness and high moisture resistance MITSUI CHEMICALS, INC. (JP) 2004-11-25 US disclosed
EP-1441013-A1 WATERCOLOR INK Mitsui Chemicals, Inc. (JP) 2004-07-28 EP disclosed