Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 4/20 | 0.49 |
| ▸ | CA9 | Q16790 | 4/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8349195 | 1.00 | SLC1A3 (0.52) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B | |
| SCHEMBL7373819 | 0.85 | SLC1A3 (0.61) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B | |
| SCHEMBL16938448 | 0.84 | CA2 (0.48) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7652619 | 0.84 | SLC1A3 (0.60) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B | |
| SCHEMBL14472431 | 0.81 | CA12 (0.45) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B | |
| SCHEMBL14542796 | 0.81 | POLB (0.47) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B | |
| SCHEMBL7397814 | 0.79 | POLB (0.50) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B | |
| SCHEMBL7315790 | 0.79 | POLB (0.50) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B | |
| SCHEMBL10054647 | 0.79 | CA12 (0.50) | ITGB3ITGA2BCA2CA12CA9 | |
| Hydrochloric Acid SCHEMBL7315786 | 0.78 | POLB (0.49) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102766-B1 | TRIAZOLOPYRIDINES FOR THE TREATMENT OF THROMBOSIS DISORDERS | ORTHO MCNEIL PHARM INC (US) | 2004-03-31 | — | — | EP | disclosed |
| US-6303625-B1 | FIBRINOGEN RECEPTOR ANTAGONISTS WHICH INHIBIT PLATELET AGGREGATION AND ARE USEFUL IN TREATING THROMBOTIC DISORDERS | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2001-10-16 | — | — | US | disclosed |
| EP-1102766-A1 | TRIAZOLOPYRIDINES FOR THE TREATMENT OF THROMBOSIS DISORDERS | Ortho-McNeil Pharmaceutical, Inc. (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000006570-A1 | TRIAZOLOPYRIDINES FOR THE TREATMENT OF THROMBOSIS DISORDERS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2000-02-10 | — | — | WO | disclosed |
| WO-1999020606-A2 | PIPERIDINES AND PIPERAZINES AS PLATELET AGGREGATION INHIBITORS | J. URIACH & CIA. S.A. (ES) | 1999-04-29 | — | — | WO | disclosed |