Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.60 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.59 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6634019 | 0.96 | ACAT1 (0.61) | ACAT1SOAT1PDE4AKCNH2 | |
| SCHEMBL6635950 | 0.92 | ACAT1 (0.68) | ACAT1SOAT1PDE4AKCNH2 | |
| SCHEMBL6634285 | 0.90 | ACAT1 (0.72) | ACAT1SOAT1PDE4AKCNH2 | |
| SCHEMBL6634517 | 0.90 | ACAT1 (0.76) | ACAT1SOAT1PDE4AKCNH2 | |
| SCHEMBL6634199 | 0.88 | ACAT1 (0.61) | ACAT1SOAT1PDE4AKCNH2 | |
| SCHEMBL6635347 | 0.88 | SOAT1 (0.66) | ACAT1SOAT1PDE4AKCNH2 | |
| SCHEMBL6633503 | 0.88 | ACAT1 (0.57) | ACAT1SOAT1 | |
| SCHEMBL6634432 | 0.88 | ACAT1 (0.61) | ACAT1SOAT1PDE4AKCNH2 | |
| SCHEMBL6636527 | 0.87 | ACAT1 (0.58) | ACAT1SOAT1 | |
| SCHEMBL6635775 | 0.86 | ACAT1 (0.76) | ACAT1SOAT1PDE4AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842933-B1 | NOVEL NAPHTHYRIDINE DERIVATIVES | SUMITOMO PHARMA (JP) | 2004-08-04 | — | — | EP | disclosed |
| US-5843957-A | Naphthyridine derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LTD. (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0842933-A1 | NOVEL NAPHTHYRIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-05-20 | — | — | EP | disclosed |