Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | DBH | P09172 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2942246 | 0.98 | CA2 (0.55) | CA2CA1CSNK2A1HSD17B10TSHR | |
| Bromide SCHEMBL1469280 | 0.98 | CA2 (0.55) | CA2CA1CSNK2A1HSD17B10TSHR | |
| SCHEMBL1466961 | 0.83 | TAAR1 (0.67) | CA2CA1HSD17B10TSHRCYP1A2 | |
| SCHEMBL13343744 | 0.82 | TDP1 (0.50) | CSNK2A1HSD17B10TSHRCYP3A4CYP2D6 | |
| SCHEMBL71042 | 0.81 | HSD17B10 (0.63) | CA2CA1HSD17B10TSHRCYP1A2 | |
| SCHEMBL9773533 | 0.81 | CA2 (0.61) | CA2CA1HSD17B10TSHRCYP1A2 | |
| Hydrochloric Acid SCHEMBL2386540 | 0.81 | MAPK1 (0.68) | CA2CA1HSD17B10TSHRCYP2D6 | |
| Bromide SCHEMBL1468106 | 0.81 | TAAR1 (0.64) | CA2CA1HSD17B10TSHRCYP1A2 | |
| Hydrochloric Acid SCHEMBL3564510 | 0.80 | TDP1 (0.48) | CSNK2A1HSD17B10TSHRCYP3A4CYP2D6 | |
| SCHEMBL507053 | 0.79 | CA2 (0.59) | CA2CA1HSD17B10TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1636998-A | Method for producing benzo annelated heterocycles | MERCK PATENT GMBH (DE) | 2005-07-13 | — | — | CN | claimed |
| EP-1280792-B1 | METHOD FOR PRODUCING BENZO ANNELATED HETEROCYCLES | MERCK PATENT GMBH (DE) | 2004-07-14 | — | — | EP | claimed |
| US-6723848-B2 | TETRAHYDROBENZOFURAN OR TETRAHYDROBENZOTHIOPHEN OR TETRAHDYROBENZOPYRROLE COMPOUNDS CAN BE AROMATIZED WITH A HYDROGENATION CATALYST IN PRESENCE OF A HYDROGEN ACCEPTOR, DEACYLATION OF AMINO GROUP BY ADDITION OF AN AMINE GROUP | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 2004-04-20 | — | — | US | claimed |
| CN-1422265-A | Process for producing benzo-fused heterocycle | MERCK PATENT GMBH (DE) | 2003-06-04 | — | — | CN | claimed |
| US-20030078422-A1 | Method for producing benzo annelated heterocycles | MERCK PATENT GMBH (DE) | 2003-04-24 | — | — | US | claimed |
| EP-1280792-A1 | METHOD FOR PRODUCING BENZO ANNELATED HETEROCYCLES | MERCK PATENT GmbH (DE) | 2003-02-05 | — | — | EP | claimed |
| WO-2001077099-A1 | METHOD FOR PRODUCING BENZO ANNELATED HETEROCYCLES | MERCK PATENT GMBH (DE) | 2001-10-18 | — | — | WO | claimed |
| CN-105473583-A | Bicyclyl-substituted isothiazoline compounds | BASF SE | 2016-04-06 | — | — | CN | disclosed |
| CN-104968666-A | Macrocyclic molecules as HCV entry inhibitors | BRISTOL MYERS SQUIBB CO | 2015-10-07 | — | — | CN | disclosed |
| CN-1993346-B | Thiophene compound | ACTELION PHARMACEUTICALS LTD | 2011-04-27 | — | — | CN | disclosed |
| CN-1993346-A | Novel thiophene derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2007-07-04 | — | — | CN | disclosed |
| CN-1214023-C | Process for producing benzo-fused heterocycle | MERCK PATENT GMBH (DE) | 2005-08-10 | — | — | CN | disclosed |
| CN-1636998-A | Method for producing benzo annelated heterocycles | MERCK PATENT GMBH (DE) | 2005-07-13 | — | — | CN | disclosed |
| US-20030078422-A1 | Method for producing benzo annelated heterocycles | MERCK PATENT GMBH (DE) | 2003-04-24 | — | — | US | disclosed |
| EP-1280792-A1 | METHOD FOR PRODUCING BENZO ANNELATED HETEROCYCLES | MERCK PATENT GmbH (DE) | 2003-02-05 | — | — | EP | disclosed |
| CN-1355805-A | Thienopyrimidines compound | MERCK PATENT GMBH (DE) | 2002-06-26 | — | — | CN | disclosed |
| EP-1189907-A1 | THIENOPYRIMIDINES AS PHOSPHODIESTERASE INHIBITORS | MERCK PATENT GmbH (DE) | 2002-03-27 | — | — | EP | disclosed |
| WO-2001077099-A1 | METHOD FOR PRODUCING BENZO ANNELATED HETEROCYCLES | MERCK PATENT GMBH (DE) | 2001-10-18 | — | — | WO | disclosed |
| WO-2000078767-A1 | THIENOPYRIMIDINES AS PHOSPHODIESTERASE INHIBITORS | MERCK PATENT GMBH (DE) | 2000-12-28 | — | — | WO | disclosed |
| US-4526962-A | Cephalosporin derivatives | RHONE-POULENC SANTE (FR) | 1985-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078422-A1 | Method for producing benzo annelated heterocycles | NAT1, AFF1, SAT1 | CA2 1257/4885CA1 765/4885CSNK2A1 1340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.