Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.51 |
| ▸ | PPARA | Q07869 | 10/20 | 0.51 |
| ▸ | POLB | P06746 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5730668 | 0.83 | PPARG (0.54) | PPARGPPARA | |
| SCHEMBL5730014 | 0.83 | PPARG (0.53) | PPARGPPARA | |
| SCHEMBL6631311 | 0.81 | PPARG (0.55) | PPARGPPARA | |
| SCHEMBL6635382 | 0.80 | PPARG (0.58) | PPARGPPARA | |
| SCHEMBL6631504 | 0.80 | PPARG (0.50) | PPARGPPARAMAPTTP53 | |
| SCHEMBL5736143 | 0.79 | PPARG (0.49) | PPARGPPARA | |
| SCHEMBL5346336 | 0.79 | PPARG (0.49) | PPARGPPARA | |
| SCHEMBL6632292 | 0.78 | PPARA (0.50) | PPARGPPARA | |
| SCHEMBL5351857 | 0.77 | TP53 (0.59) | PPARGPPARAMAPTTP53 | |
| SCHEMBL5730171 | 0.77 | PPARG (0.62) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401434-A1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | ELI LILLY AND COMPANY (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002100403-A1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | ELI LILLY AND COMPANY (US) | 2002-12-19 | — | — | WO | disclosed |