Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6750894 | 0.83 | KDR (0.40) | KDRFLT1 | |
| SCHEMBL14409826 | 0.79 | KDR (0.48) | KDRFLT1 | |
| SCHEMBL5242243 | 0.79 | KDR (0.48) | KDRFLT1 | |
| SCHEMBL6751239 | 0.79 | KDR (0.39) | KDRFLT1 | |
| SCHEMBL6632827 | 0.77 | KDR (0.40) | KDRFLT1 | |
| SCHEMBL6749189 | 0.77 | KDR (0.39) | KDRFLT1 | |
| SCHEMBL6753076 | 0.77 | KDR (0.40) | KDRFLT1 | |
| SCHEMBL6638049 | 0.76 | KDR (0.40) | KDRFLT1 | |
| SCHEMBL5242968 | 0.74 | KDR (0.46) | KDRFLT1 | |
| SCHEMBL14409882 | 0.73 | KDR (0.43) | KDRFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1483268-A2 | INDOLYL-UREA DERIVATIVES OF THIENOPYRIDINES USEFUL AS ANTI-ANGIOGENIC AGENTS | PFIZER INC. (US) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003074529-A2 | iNDOLYL-UREA DERIVATIVES OF THIENOPYRIDINES USEFUL AS ANTI-ANGIOGENIC AGENTS | PFIZER INC. (US) | 2003-09-12 | — | — | WO | disclosed |