Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.45 |
| ▸ | HTR2C | P28335 | 5/20 | 0.45 |
| ▸ | HTR2B | P41595 | 5/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 11/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804015 | 0.85 | SMO (0.47) | SMO | |
| SCHEMBL6804937 | 0.83 | SMO (0.56) | SMO | |
| SCHEMBL6685612 | 0.79 | S1PR1 (0.46) | HTR2AHTR2CHTR2BS1PR1S1PR3 | |
| SCHEMBL6666202 | 0.79 | S1PR1 (0.47) | HTR2AHTR2CHTR2BS1PR1S1PR3 | |
| SCHEMBL6665670 | 0.78 | S1PR1 (0.48) | HTR2AHTR2CHTR2BS1PR1S1PR3 | |
| SCHEMBL6642122 | 0.77 | S1PR1 (0.48) | S1PR1S1PR3 | |
| SCHEMBL6682828 | 0.77 | S1PR1 (0.46) | HTR2AHTR2CHTR2BS1PR1S1PR3 | |
| SCHEMBL6639642 | 0.76 | SMO (0.45) | HTR2AHTR2CHTR2BS1PR1S1PR3 | |
| SCHEMBL6638338 | 0.76 | S1PR1 (0.43) | HTR2AHTR2CHTR2BS1PR1S1PR3 | |
| SCHEMBL6683684 | 0.75 | HTR2A (0.47) | HTR2AHTR2CHTR2BS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |