Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 13/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | SMO | Q99835 | 2/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685612 | 0.88 | S1PR1 (0.46) | S1PR1S1PR3HTR2AHTR2CHTR2B | |
| SCHEMBL6679166 | 0.84 | GRM4 (0.48) | S1PR1S1PR3TRPV1 | |
| SCHEMBL6681703 | 0.82 | S1PR1 (0.44) | S1PR1S1PR3NTRK1 | |
| SCHEMBL6683684 | 0.82 | HTR2A (0.47) | S1PR1S1PR3HTR2AHTR2CHTR2B | |
| SCHEMBL6488609 | 0.80 | SMO (0.53) | SMOTRPV1 | |
| SCHEMBL6638338 | 0.80 | S1PR1 (0.43) | S1PR1S1PR3HTR2AHTR2CHTR2B | |
| SCHEMBL6683660 | 0.80 | S1PR1 (0.48) | S1PR1S1PR3 | |
| SCHEMBL6793867 | 0.79 | HTT (0.62) | SMO | |
| SCHEMBL6666202 | 0.79 | S1PR1 (0.47) | S1PR1S1PR3HTR2AHTR2CHTR2B | |
| SCHEMBL6677363 | 0.79 | NPC1 (0.48) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |