Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.51 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.51 |
| ▸ | FURIN | P09958 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799799 | 0.86 | PARP10 (0.64) | MEN1KMT2APARP10ALDH1A1PARP15 | |
| SCHEMBL11482261 | 0.84 | AKR1C3 (0.60) | MEN1KMT2AAKR1C3PARP10ALDH1A1 | |
| Carbamic Acid Phenyl Ester SCHEMBL7566 | 0.81 | MEN1 (0.70) | MEN1KMT2APARP10KDM4EHSD17B10 | |
| SCHEMBL5040450 | 0.81 | CYP3A4 (0.61) | AKR1C3ALDH1A1KDM4EHSD17B10HDAC8 | |
| SCHEMBL22557901 | 0.81 | MEN1 (0.70) | MEN1KMT2AALOX5 | |
| SCHEMBL30545116 | 0.81 | MEN1 (0.70) | MEN1KMT2AALOX5 | |
| SCHEMBL23174953 | 0.80 | KMT2A (0.62) | MEN1KMT2AAKR1C3PARP10ALDH1A1 | |
| SCHEMBL11482355 | 0.79 | KMT2A (0.56) | MEN1KMT2AAKR1C3PARP10ALDH1A1 | |
| Carbamic Acid Phenyl Ester SCHEMBL11792763 | 0.79 | MEN1 (0.67) | MEN1KMT2APARP10KDM4EHSD17B10 | |
| Carbamic Acid Phenyl Ester SCHEMBL28935973 | 0.79 | MEN1 (0.67) | MEN1KMT2APARP10KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458375-A2 | COMPOSITIONS FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051842-A2 | COMPOSITIONS DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2003-06-26 | — | — | WO | disclosed |