SCHEMBL5799799

SCHEMBL5799799

NC(=O)Oc1ccc(Oc2ccccc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 4/20 0.64
KMT2A Q03164 2/20 0.59
MEN1 O00255 1/20 0.59
LTA4H P09960 2/20 0.52
TSHR P16473 1/20 0.52
NR1H2 P55055 1/20 0.52
BAX Q07812 1/20 0.52
MAOA P21397 1/20 0.52
SRD5A2 P31213 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.51
PARP15 Q460N3 2/20 0.50
ALDH1A1 P00352 1/20 0.50
PARP14 Q460N5 1/20 0.50
PARP16 Q8N5Y8 1/20 0.50
PARP11 Q9NR21 1/20 0.50
PARP4 Q9UKK3 1/20 0.50
CTNNB1 P35222 1/20 0.50
FFAR1 O14842 1/20 0.48
SOS1 Q07889 1/20 0.48
CA1 P00915 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid Phenyl Ester SCHEMBL7566 0.91 MEN1 (0.70) PARP10KMT2AMEN1TSHRCTNNB1
Carbamic Acid Phenyl Ester SCHEMBL11627152 0.89 MEN1 (0.67) PARP10KMT2AMEN1TSHRSMN1; SMN2
Carbamic Acid Phenyl Ester SCHEMBL17144965 0.89 MEN1 (0.67) PARP10KMT2AMEN1TSHRSMN1; SMN2
Carbamic Acid Phenyl Ester SCHEMBL28935973 0.89 MEN1 (0.67) PARP10KMT2AMEN1TSHRSMN1; SMN2
Carbamic Acid Phenyl Ester SCHEMBL5447519 0.89 MEN1 (0.67) PARP10KMT2AMEN1TSHRSMN1; SMN2
Carbamic Acid Phenyl Ester SCHEMBL11792763 0.89 MEN1 (0.67) PARP10KMT2AMEN1TSHRSMN1; SMN2
SCHEMBL6636216 0.86 MEN1 (0.77) PARP10KMT2AMEN1LTA4HTSHR
Carbamic Acid Phenyl Ester SCHEMBL29517957 0.84 MEN1 (0.61) PARP10KMT2AMEN1TSHRCTNNB1
Diphenylether SCHEMBL10618785 0.84 PARP10 (0.71) PARP10KMT2ALTA4HTSHRNR1H2
Diphenylether SCHEMBL8165466 0.84 PARP10 (0.71) PARP10KMT2ALTA4HTSHRNR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3527593-B1 ISOCYANATE COMPOSITION, METHOD FOR PRODUCING ISOCYANATE COMPOSITION, AND METHOD FOR PRODUCING ISOCYANATE POLYMER ASAHI CHEMICAL IND (JP) 2025-07-23 EP disclosed
CN-111819172-B Triazine derivatives for the treatment of neurotrophin related diseases 阿泽克制药公司 2024-02-06 CN disclosed
CN-111825620-B Carbamate derivative and preparation method and application thereof 河南科技大学 2022-02-15 CN disclosed
CN-112209875-B 6-amino-4- (4-phenoxyphenethylamino) quinazoline derivative and preparation method and application thereof 绍兴文理学院 2021-11-30 CN disclosed
US-11118001-B2 Isocyanate composition, method for producing isocyanate composition, and method for producing isocyanate polymer ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-09-14 US disclosed
US-11078321-B2 2021-08-03 US disclosed
CN-112209875-A 6-amino-4- (4-phenoxyphenethylamino) quinazoline derivative and preparation method and application thereof 绍兴文理学院 2021-01-12 CN disclosed
CN-111825620-A Carbamate derivative and preparation method and application thereof 河南科技大学 2020-10-27 CN disclosed
CN-111819172-A Triazine derivatives for the treatment of neurotrophin-related disorders 阿泽克制药公司 2020-10-23 CN disclosed
WO-2006060082-A1 TRICYCLIC COMPOUNDS, PREPARATION THEREOF AND USE THEREOF AS CHOLINESTERASE ACTIVITY INHIBITORS THE GOVERNMENT OF THE U.S.A. as represented by THE SEC., DEPT. OF HEALTH & HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH (US) 2006-06-08 WO disclosed
US-5152827-A Substituted phenyl carbamates and their use as herbicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-10-06 US disclosed
US-5099059-A Phenoxyalkylcarbamates ZENECA LIMITED (GB) 1992-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11078321-B2 IDH3A, IPO4, F12 PARP10 1593/4885KMT2A 2978/4885MEN1 1259/4885
US-11118001-B2 Isocyanate composition, method for producing isocyanate composition, and method for producing isocyanate polymer IDH3A, IPO4, IDH3B PARP10 1454/4885KMT2A 2763/4885MEN1 1433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.