Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7003683 | 0.66 | — | — | |
| SCHEMBL8621745 | 0.62 | GSK3A (0.32) | GSK3AGSK3B | |
| SCHEMBL7426675 | 0.61 | GSK3A (0.31) | GSK3AGSK3B | |
| SCHEMBL18797843 | 0.61 | — | — | |
| SCHEMBL11646982 | 0.57 | — | — | |
| SCHEMBL19472118 | 0.53 | NQO1 (0.33) | — | |
| SCHEMBL10372116 | 0.53 | NQO1 (0.31) | — | |
| Carbon Monoxide SCHEMBL5588303 | 0.52 | GSK3A (0.59) | GSK3AGSK3B | |
| SCHEMBL6689962 | 0.51 | — | — | |
| SCHEMBL12336961 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397361-A1 | CARBOLINE DERIVATIVES AS PDEV INHIBITORS | Lilly Icos LLC (US) | 2004-03-17 | — | — | EP | disclosed |
| EP-1313736-A2 | CONDENSED PYRAZINDIONE DERIVATIVES | Lilly Icos LLC (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2003000691-A1 | CARBOLINE DERIVATIVES AS PDEV INHIBITORS | LILLY ICOS LLC (US) | 2003-01-03 | — | — | WO | disclosed |
| WO-2002000657-A2 | CONDENSED PYRAZINDIONE DERIVATIVES | LILLY ICOS LLC (US) | 2002-01-03 | — | — | WO | disclosed |