Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27418836 | 0.81 | MEN1 (0.51) | KMT2AMEN1RAB9ANPC1HDAC1 | |
| SCHEMBL8527697 | 0.81 | MEN1 (0.55) | KMT2AMEN1RAB9ANPC1HDAC1 | |
| SCHEMBL4520729 | 0.81 | MEN1 (0.54) | KMT2AMEN1RAB9ANPC1HDAC1 | |
| SCHEMBL8088590 | 0.79 | MEN1 (0.51) | KMT2AMEN1RAB9ANPC1USP2 | |
| SCHEMBL665932 | 0.79 | MEN1 (0.56) | KMT2AMEN1RAB9ANPC1USP2 | |
| SCHEMBL20054193 | 0.78 | MEN1 (0.51) | KMT2AMEN1RAB9ANPC1HDAC1 | |
| SCHEMBL4916450 | 0.78 | MEN1 (0.48) | KMT2AMEN1RAB9ANPC1USP2 | |
| SCHEMBL20931418 | 0.78 | KMT2A (0.62) | KMT2AMEN1RAB9ANPC1USP2 | |
| SCHEMBL15303762 | 0.78 | MEN1 (0.48) | KMT2AMEN1RAB9ANPC1USP2 | |
| SCHEMBL11130003 | 0.77 | MEN1 (0.47) | KMT2AMEN1RAB9ANPC1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116924964-A | Preparation method of tetrahydrocarbazole ring compound | 四川轻化工大学 | 2023-10-24 | — | — | CN | claimed |
| US-6391917-B1 | ANALGESIC | ZYMOGENETICS, INC. | 2002-05-21 | — | — | US | claimed |
| US-6255351-B1 | TREATMENT OF BONE DISORDERS | ZYMOGENETICS, INC. | 2001-07-03 | — | — | US | claimed |
| US-6221913-B1 | Dialkyl ureas as calcitonin mimetics | ZYMOGENETICS, INC. | 2001-04-24 | — | — | US | claimed |
| US-6143932-A | FOR EFFECTING ANALGESIA, A DECREASE IN THE POSTPRANDIAL RISE IN THE BLOOD GLUCOSE LEVELS OF A MAMMAL AFTER INGESTION OF A CARBOHYDRATE LOAD BY SAID MAMMAL, AND TREATING MICROBIAL INFECTIONS | TREGA BIOSCIENCES, INC. (US) | 2000-11-07 | — | — | US | claimed |
| EP-0975589-A2 | DIALKYL UREAS AS CALCITONIN MIMETICS | ZymoGenetics, Inc. (US) | 2000-02-02 | — | — | EP | claimed |
| WO-1999037604-A2 | DIALKYL UREAS AS CALCITONIN MIMETICS | ZYMOGENETICS, INC. (US) | 1999-07-29 | — | — | WO | claimed |
| US-5859190-A | SOLID PHASE SYNTHESIS TO FORM A PROTECTED DIPEPTIDE FOLLOWED BY REACTING WITH 1,1'-THIOCARBONYLDIIMIDAZOLE TO EFFECT RING FORMATION; EFFICIENCY; ANTICONVULSANT,-ARRHYTHMIC AND DIABETIC AGENTS; HERBICIDES AND FUNGICIDES | TREGA BIOSCIENCES, INC. (US) | 1999-01-12 | — | — | US | claimed |
| WO-1998033776-A1 | COMBINATORIAL LIBRARIES OF HYDANTOIN AND THIOHYDANTOIN DERIVATIVES, METHODS OF MAKING THE LIBRARIES AND COMPOUNDS THEREIN | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | claimed |
| CN-116924964-A | Preparation method of tetrahydrocarbazole ring compound | 四川轻化工大学 | 2023-10-24 | — | — | CN | disclosed |
| EP-3733428-B1 | FUNCTIONALIZED ALUMINUM REAGENTS, METHOD OF MAKING A FUNCTIONALIZED ELASTOMER, ELASTOMER, RUBBER COMPOSITION AND TIRE | GOODYEAR TIRE & RUBBER (US) | 2022-03-16 | — | — | EP | disclosed |
| EP-3733428-A1 | FUNCTIONALIZED ALUMINUM REAGENTS, METHOD OF MAKING A FUNCTIONALIZED ELASTOMER, ELASTOMER, RUBBER COMPOSITION AND TIRE | The Goodyear Tire & Rubber Company (US) | 2020-11-04 | — | — | EP | disclosed |
| US-10711016-B1 | Functionalized aluminum reagents | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2020-07-14 | — | — | US | disclosed |
| CN-108101830-B | A kind of 3- replaces the preparation method of Oxoindole and derivative | 中国科学院成都生物研究所 | 2019-08-23 | — | — | CN | disclosed |
| US-6143932-A | FOR EFFECTING ANALGESIA, A DECREASE IN THE POSTPRANDIAL RISE IN THE BLOOD GLUCOSE LEVELS OF A MAMMAL AFTER INGESTION OF A CARBOHYDRATE LOAD BY SAID MAMMAL, AND TREATING MICROBIAL INFECTIONS | TREGA BIOSCIENCES, INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-6121489-A | Selectively N-alkylated peptidomimetic combinatorial libraries and compounds therein | TREGA BIOSCIENCES, INC. (US) | 2000-09-19 | — | — | US | disclosed |
| EP-0975589-A2 | DIALKYL UREAS AS CALCITONIN MIMETICS | ZymoGenetics, Inc. (US) | 2000-02-02 | — | — | EP | disclosed |
| WO-1999037604-A2 | DIALKYL UREAS AS CALCITONIN MIMETICS | ZYMOGENETICS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |
| US-5859190-A | SOLID PHASE SYNTHESIS TO FORM A PROTECTED DIPEPTIDE FOLLOWED BY REACTING WITH 1,1'-THIOCARBONYLDIIMIDAZOLE TO EFFECT RING FORMATION; EFFICIENCY; ANTICONVULSANT,-ARRHYTHMIC AND DIABETIC AGENTS; HERBICIDES AND FUNGICIDES | TREGA BIOSCIENCES, INC. (US) | 1999-01-12 | — | — | US | disclosed |
| WO-1998033776-A1 | COMBINATORIAL LIBRARIES OF HYDANTOIN AND THIOHYDANTOIN DERIVATIVES, METHODS OF MAKING THE LIBRARIES AND COMPOUNDS THEREIN | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10711016-B1 | Functionalized aluminum reagents | C3AR1, FCGRT, ALK | KMT2A 397/4885MEN1 318/4885RAB9A 1574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.