Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15241823 | 0.86 | MEN1 (0.54) | MEN1KMT2ANR4A2HDAC1HDAC2 | |
| SCHEMBL10865240 | 0.85 | ALDH1A1 (0.55) | MEN1KMT2ANR4A2MAPTBRCA1 | |
| SCHEMBL8612793 | 0.84 | CNR2 (0.56) | MEN1KMT2AALDH1A1POLB | |
| SCHEMBL4520729 | 0.82 | MEN1 (0.54) | MEN1KMT2AHDAC1HDAC2HDAC8 | |
| SCHEMBL8186052 | 0.82 | MEN1 (0.58) | MEN1KMT2ANR4A2HDAC1HDAC2 | |
| SCHEMBL12206640 | 0.81 | CNR2 (0.54) | MEN1KMT2AALDH1A1 | |
| SCHEMBL20221429 | 0.80 | MEN1 (0.53) | MEN1KMT2AHDAC1HDAC2HDAC8 | |
| SCHEMBL7712112 | 0.80 | CNR2 (0.59) | — | |
| SCHEMBL10396791 | 0.79 | NR4A2 (0.51) | MEN1KMT2ANR4A2MAPTBRCA1 | |
| SCHEMBL11622484 | 0.79 | MEN1 (0.55) | MEN1KMT2AHDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6391917-B1 | ANALGESIC | ZYMOGENETICS, INC. | 2002-05-21 | — | — | US | claimed |
| US-6255351-B1 | TREATMENT OF BONE DISORDERS | ZYMOGENETICS, INC. | 2001-07-03 | — | — | US | claimed |
| US-6221913-B1 | Dialkyl ureas as calcitonin mimetics | ZYMOGENETICS, INC. | 2001-04-24 | — | — | US | claimed |
| US-6143932-A | FOR EFFECTING ANALGESIA, A DECREASE IN THE POSTPRANDIAL RISE IN THE BLOOD GLUCOSE LEVELS OF A MAMMAL AFTER INGESTION OF A CARBOHYDRATE LOAD BY SAID MAMMAL, AND TREATING MICROBIAL INFECTIONS | TREGA BIOSCIENCES, INC. (US) | 2000-11-07 | — | — | US | claimed |
| EP-0975589-A2 | DIALKYL UREAS AS CALCITONIN MIMETICS | ZymoGenetics, Inc. (US) | 2000-02-02 | — | — | EP | claimed |
| EP-0890101-A4 | SELECTIVELY N-ALKYLATED PEPTIDOMIMETIC COMBINATORIAL LIBRARIES AND COMPOUNDS THEREIN | TORREY PINES INST (US) | 1999-12-08 | — | — | EP | claimed |
| WO-1999037604-A2 | DIALKYL UREAS AS CALCITONIN MIMETICS | ZYMOGENETICS, INC. (US) | 1999-07-29 | — | — | WO | claimed |
| EP-0890101-A1 | SELECTIVELY N-ALKYLATED PEPTIDOMIMETIC COMBINATORIAL LIBRARIES AND COMPOUNDS THEREIN | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1999-01-13 | — | — | EP | claimed |
| US-5859190-A | SOLID PHASE SYNTHESIS TO FORM A PROTECTED DIPEPTIDE FOLLOWED BY REACTING WITH 1,1'-THIOCARBONYLDIIMIDAZOLE TO EFFECT RING FORMATION; EFFICIENCY; ANTICONVULSANT,-ARRHYTHMIC AND DIABETIC AGENTS; HERBICIDES AND FUNGICIDES | TREGA BIOSCIENCES, INC. (US) | 1999-01-12 | — | — | US | claimed |
| EP-0457195-B1 | Peptides having endothelin antagonist activity, a process for preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-04-15 | — | — | EP | claimed |
| WO-1997033174-A1 | SELECTIVELY N-ALKYLATED PEPTIDOMIMETIC COMBINATORIAL LIBRARIES AND COMPOUNDS THEREIN | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1997-09-12 | — | — | WO | claimed |
| US-5656604-A | HYPOTENSIVE AGENT; ENDOTHELIN ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | claimed |
| US-5430022-A | Endothelin antagonists; hypotensive agents; treatment for angina pectoris, brain disorders, asthma, renal failure | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-07-04 | — | — | US | claimed |
| US-5284828-A | Hypotensive agents | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 1994-02-08 | — | — | US | claimed |
| CN-1057269-A | Peptide compounds and preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-12-25 | — | — | CN | claimed |
| EP-0457195-A2 | Peptides having endothelin antagonist activity, a process for preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-11-21 | — | — | EP | claimed |
| WO-2023109932-A1 | DSRNA AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海拓界生物医药科技有限公司 | 2023-06-22 | — | — | WO | disclosed |
| US-20220306654-A1 | MECHANOREDOX REACTION USING PIEZOELECTRIC MATERIAL, AND PRODUCTION METHOD USING SAID REACTION | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2022-09-29 | — | — | US | disclosed |
| US-4443615-A | ANILINE, GLYCOL OR EPOXIDE, SILICA AND/OR ALUMINA CATALYST | TANABE SEIYAKU CO., LTD. (JP) | 1984-04-17 | — | — | US | disclosed |
| US-4072519-A | Photoconductive composition, and element | XEROX CORPORATION (US) | 1978-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220306654-A1 | MECHANOREDOX REACTION USING PIEZOELECTRIC MATERIAL, AND PRODUCTION METHOD USING SAID REACTION | PIEZO1, PPOX, TAOK1 | MEN1 269/4885KMT2A 3932/4885NR4A2 3344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.