Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 5/20 | 0.55 |
| ▸ | CASP2 | P42575 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3357547 | 1.00 | HSP90AA1 (0.57) | HSP90AA1FAAHCASP2HDAC3HDAC1 | |
| SCHEMBL6641767 | 0.96 | HSP90AA1 (0.57) | HSP90AA1FAAHCASP2HDAC3HDAC1 | |
| SCHEMBL6636541 | 0.96 | CASP2 (0.53) | HSP90AA1FAAHCASP2HDAC3HDAC1 | |
| SCHEMBL15277703 | 0.93 | HSP90AA1 (0.50) | HSP90AA1FAAHCASP2HDAC3HDAC1 | |
| SCHEMBL2416986 | 0.92 | HDAC3 (0.61) | HSP90AA1FAAHCASP2HDAC3HDAC1 | |
| SCHEMBL249559 | 0.92 | HDAC3 (0.61) | HSP90AA1FAAHCASP2HDAC3HDAC1 | |
| SCHEMBL248584 | 0.92 | HDAC3 (0.61) | HSP90AA1FAAHCASP2HDAC3HDAC1 | |
| SCHEMBL19060553 | 0.92 | CASP2 (0.64) | HSP90AA1FAAHCASP2HDAC3HDAC1 | |
| SCHEMBL4662735 | 0.92 | HDAC3 (0.61) | HSP90AA1FAAHCASP2HDAC3HDAC1 | |
| SCHEMBL119271 | 0.92 | HDAC3 (0.61) | HSP90AA1FAAHCASP2HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420044-A2 | Rubber composition and pneumatic tire | Bridgestone Corporation (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6380288-B1 | LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS | BRIDGESTONE CORPORATION | 2002-04-30 | — | — | US | disclosed |
| EP-0909788-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | Bridgestone Corporation (JP) | 1999-04-21 | — | — | EP | disclosed |