Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6635420 | 0.92 | F2 (0.37) | F2POLBF10GAAMAPT | |
| SCHEMBL6635827 | 0.89 | HIF1A (0.37) | HIF1AALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL6632766 | 0.80 | HIF1A (0.42) | F2HIF1APOLBF10MAPT | |
| SCHEMBL6636352 | 0.75 | F2 (0.39) | F2ALDH1A1LMNAF10MAPT | |
| SCHEMBL6635644 | 0.74 | F2 (0.43) | F2HIF1AALDH1A1PKMF10 | |
| SCHEMBL6634047 | 0.73 | F2 (0.58) | F2ALDH1A1LMNANPSR1PKM | |
| SCHEMBL6632770 | 0.70 | TSHR (0.40) | F2ALDH1A1LMNANPSR1POLB | |
| SCHEMBL6636555 | 0.69 | F2 (0.58) | F2ALDH1A1LMNAPKMGAA | |
| Hydrochloric Acid SCHEMBL6636009 | 0.68 | F2 (0.57) | F2ALDH1A1LMNAPKMGAA | |
| SCHEMBL6638862 | 0.68 | HIF1A (0.44) | HIF1APOLBMAPTHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100795-B1 | DISUBSTITUTED BICYCLIC HETEROCYCLES HAVING, IN PARTICULAR, A THROMBIN INHIBITIVE EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-06-09 | — | — | EP | disclosed |
| US-6121308-A | INDOLE AND BENZIMIDAZOLE ANTITHROMBOTIC COMPOUNDS, SUCH AS 1-METHYL-2-(N-(4-AMIDINOPHENYL)-AMINOMETHYL)-5-(N-(HYDROXYCARBONYLMETHYL) -QUINOLINE-8-SULPHONYLAMINO)-INDOLE | BOEHRINGER INGELHEIM KG (DE) | 2000-09-19 | — | — | US | disclosed |