Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17A | Q9UEE5 | 12/20 | 0.49 |
| ▸ | STK17B | O94768 | 7/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | BCL6 | P41182 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | ULK1 | O75385 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1916749 | 0.84 | STK17A (0.50) | STK17ASTK17BBRD4HDAC3HDAC1 | |
| Hydrochloric Acid SCHEMBL1916778 | 0.83 | STK17A (0.49) | STK17ASTK17BBRD4HDAC3HDAC1 | |
| SCHEMBL16450210 | 0.71 | TBK1 (0.48) | AURKA | |
| SCHEMBL1917907 | 0.70 | STK17A (0.53) | STK17ASTK17BBRD4HDAC3HDAC1 | |
| SCHEMBL1918252 | 0.70 | STK17A (0.53) | STK17ASTK17BBRD4HDAC3HDAC1 | |
| SCHEMBL5408742 | 0.69 | STK17A (0.58) | STK17ASTK17BBRD4HDAC3HDAC1 | |
| SCHEMBL1917265 | 0.68 | SRC (0.49) | STK17ASTK17BHDAC3HDAC1HDAC2 | |
| SCHEMBL5402321 | 0.67 | STK17A (0.55) | STK17ASTK17BBRD4HDAC3HDAC1 | |
| SCHEMBL1916395 | 0.67 | CHEK1 (0.54) | STK17ASTK17BAURKAULK1 | |
| SCHEMBL20154739 | 0.66 | STK17A (1.00) | STK17ASTK17B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1438053-A1 | PYRIMIDINE DERIVATIVES, PHARMACEUTICAL AGENT CONTAINING SAID COMPOUNDS, USE AND METHOD FOR MAKING SAME | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-07-21 | — | — | EP | disclosed |
| WO-2003032997-A1 | PYRIMIDINE DERIVATIVES, PHARMACEUTICAL AGENT CONTAINING SAID COMPOUNDS, USE AND METHOD FOR MAKING SAME | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-04-24 | — | — | WO | disclosed |