Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | USP2 | O75604 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.60 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.60 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | S100A4 | P26447 | 1/20 | 0.53 |
| ▸ | GSTP1 | P09211 | 8/20 | 0.47 |
| ▸ | GSTM2 | P28161 | 8/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3040278 | 0.84 | MEN1 (0.61) | MEN1KMT2AUSP2POLBTNNI3 | |
| SCHEMBL6636717 | 0.82 | MEN1 (0.58) | MEN1KMT2AUSP2POLBTNNI3 | |
| SCHEMBL9285207 | 0.82 | MEN1 (0.62) | MEN1KMT2AUSP2POLBTNNI3 | |
| SCHEMBL9282535 | 0.81 | MEN1 (0.60) | MEN1KMT2AUSP2POLBTNNI3 | |
| SCHEMBL9282541 | 0.81 | MEN1 (0.60) | MEN1KMT2AUSP2POLBTNNI3 | |
| SCHEMBL29443251 | 0.81 | MEN1 (0.60) | MEN1KMT2AUSP2POLBTNNI3 | |
| SCHEMBL3500025 | 0.76 | MEN1 (0.97) | MEN1KMT2AUSP2POLBTNNI3 | |
| SCHEMBL3505138 | 0.75 | MEN1 (1.00) | MEN1KMT2AUSP2POLBTNNI3 | |
| SCHEMBL12849477 | 0.73 | MEN1 (0.67) | MEN1KMT2AUSP2POLBTNNI3 | |
| SCHEMBL12383575 | 0.72 | MEN1 (0.49) | MEN1KMT2AUSP2POLBTNNI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067894-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-09-08 | — | — | EP | claimed |
| US-6518267-B1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-02-11 | — | — | US | claimed |
| EP-1067894-A2 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2001-01-17 | — | — | EP | claimed |
| WO-1999059526-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-25 | — | — | WO | claimed |
| EP-1067894-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-09-08 | — | — | EP | disclosed |
| US-6518267-B1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-02-11 | — | — | US | disclosed |
| EP-1067894-A2 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999059526-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-25 | — | — | WO | disclosed |