Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.62 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.62 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | S100A4 | P26447 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | GSTP1 | P09211 | 5/20 | 0.46 |
| ▸ | GSTM2 | P28161 | 5/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | MYC | P01106 | 3/20 | 0.42 |
| ▸ | MAX | P61244 | 1/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9282541 | 0.89 | MEN1 (0.60) | MEN1KMT2AUSP2POLBTNNI3 | |
| SCHEMBL29443251 | 0.89 | MEN1 (0.60) | MEN1KMT2AUSP2POLBTNNI3 | |
| SCHEMBL9282535 | 0.89 | MEN1 (0.60) | MEN1KMT2AUSP2POLBTNNI3 | |
| SCHEMBL3040278 | 0.83 | MEN1 (0.61) | MEN1KMT2AUSP2POLBTNNI3 | |
| SCHEMBL6636721 | 0.82 | MEN1 (0.60) | MEN1KMT2AUSP2POLBTNNI3 | |
| SCHEMBL6636717 | 0.81 | MEN1 (0.58) | MEN1KMT2AUSP2POLBTNNI3 | |
| SCHEMBL12383575 | 0.80 | MEN1 (0.49) | MEN1KMT2AUSP2POLBTNNI3 | |
| SCHEMBL15101231 | 0.80 | KMT2A (0.67) | MEN1KMT2AUSP2POLBTNNI3 | |
| SCHEMBL3505138 | 0.77 | MEN1 (1.00) | MEN1KMT2AUSP2POLBTNNI3 | |
| SCHEMBL7978483 | 0.76 | SMN1; SMN2 (0.68) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7188224-A | — | — | None | — | — | JP | disclosed |
| JP-H07188224-A | NEW OPTICALLY ACTIVE (R)-(+)-AND (S)-(-)-4-(2-CHLOROFORMYLPYRROLIDIN-1-YL)-7-NITRO-2,1,3-BENZOXAZIAZOLE | TOKYO KASEI KOGYO KK | 1995-07-25 | — | — | JP | disclosed |