⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31378327 | 0.76 | TSHR (0.35) | — | |
| SCHEMBL2874853 | 0.73 | — | — | |
| SCHEMBL8417554 | 0.69 | — | — | |
| Tert-Butanol SCHEMBL8182860 | 0.67 | ALDH1A1 (0.35) | — | |
| SCHEMBL41401 | 0.66 | — | — | |
| SCHEMBL5409330 | 0.66 | — | — | |
| SCHEMBL11575445 | 0.65 | — | — | |
| SCHEMBL23495442 | 0.62 | — | — | |
| SCHEMBL1985723 | 0.62 | — | — | |
| Bromide SCHEMBL6722331 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9714206-B2 | Methyl-iodide-free carbonylation of an alcohol to its homologous aldehyde and/or alcohol | EASTMAN CHEMICAL COMPANY (US) | 2017-07-25 | — | — | US | claimed |
| US-20160185701-A1 | METHYL-IODIDE-FREE CARBONYLATION OF AN ALCOHOL TO ITS HOMOLOGOUS ALDEHYDE AND/OR ALCOHOL | EASTMAN CHEMICAL COMPANY (US) | 2016-06-30 | — | — | US | claimed |
| US-9266806-B1 | Reductive carbonylation of methanol to acetaldehyde | EASTMAN CHEMICAL COMPANY (US) | 2016-02-23 | — | — | US | claimed |
| US-9238606-B1 | Methyl-Iodide-free carbonylation of methanol to acetaldehyde | EASTMAN CHEMICAL COMPANY (US) | 2016-01-19 | — | — | US | claimed |
| US-8829248-B2 | Method for recovery and recycle of ruthenium homogeneous catalysts | EASTMAN CHEMICAL COMPANY (US) | 2014-09-09 | — | — | US | claimed |
| EP-2605856-A1 | METHOD FOR RECOVERY AND RECYCLE OF RUTHENIUM HOMOGENEOUS CATALYSTS | Eastman Chemical Company (US) | 2013-06-26 | — | — | EP | claimed |
| WO-2012024253-A1 | METHOD FOR RECOVERY AND RECYCLE OF RUTHENIUM HOMOGENEOUS CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2012-02-23 | — | — | WO | claimed |
| US-20120046481-A1 | METHOD FOR RECOVERY AND RECYCLE OF RUTHENIUM HOMOGENEOUS CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2012-02-23 | — | — | US | claimed |
| US-9718754-B2 | Methyl-iodide-free carbonylation of an alcohol to its homologous aldehyde and/or alcohol | EASTMAN CHEMICAL COMPANY (US) | 2017-08-01 | — | — | US | disclosed |
| US-9714206-B2 | Methyl-iodide-free carbonylation of an alcohol to its homologous aldehyde and/or alcohol | EASTMAN CHEMICAL COMPANY (US) | 2017-07-25 | — | — | US | disclosed |
| CN-104203884-B | Passivation of homogeneous hydrogenation catalysts for the production of ethylene glycol | 伊士曼化工公司 | 2017-04-05 | — | — | CN | disclosed |
| US-20160251292-A1 | METHYL-IODIDE-FREE CARBONYLATION OF AN ALCOHOL TO ITS HOMOLOGOUS ALDEHYDE AND/OR ALCOHOL | EASTMAN CHEMICAL COMPANY (US) | 2016-09-01 | — | — | US | disclosed |
| US-20160185701-A1 | METHYL-IODIDE-FREE CARBONYLATION OF AN ALCOHOL TO ITS HOMOLOGOUS ALDEHYDE AND/OR ALCOHOL | EASTMAN CHEMICAL COMPANY (US) | 2016-06-30 | — | — | US | disclosed |
| US-20160185700-A1 | METHYL-IODIDE-FREE CARBONYLATION OF AN ALCOHOL TO ITS HOMOLOGOUS ALDEHYDE AND/OR ALCOHOL | EASTMAN CHEMICAL COMPANY (US) | 2016-06-30 | — | — | US | disclosed |
| US-6337297-B1 | CHROMIUM CATALYST FOR TRIMERIZATION OF ETHYLENE WITH MULTIDENTATE LIGAND OR HALOGEN, CARBOXY GROUP | TOSOH CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| US-5968866-A | CHROMIUM COMPLEXES WITH POLYDENTAE PHOSPHINE, ARSINE OR STIBINE LIGAND | BP AMOCO CORPORATION (US) | 1999-10-19 | — | — | US | disclosed |
| US-5811618-A | Ethylene trimerization | AMOCO CORPORATION (US) | 1998-09-22 | — | — | US | disclosed |
| EP-0622347-B1 | Ethylene trimerisation and catalysts therefor | AMOCO CORP (US) | 1998-06-10 | — | — | EP | disclosed |
| US-5550305-A | HEXENE/1-/; USING COORDINATION CATALYST | AMOCO CORPORATION (US) | 1996-08-27 | — | — | US | disclosed |
| EP-0622347-A1 | Ethylene trimerisation and catalysts therefor | ALBEMARLE CORPORATION (US) | 1994-11-02 | — | — | EP | disclosed |