Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.80 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.72 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6636924 | 1.00 | AGTR1 (0.80) | AGTR1ABCC3ABCC2 | |
| SCHEMBL9593060 | 0.94 | AGTR1 (0.79) | AGTR1ABCC3ABCC2 | |
| SCHEMBL9593073 | 0.94 | AGTR1 (0.79) | AGTR1ABCC3ABCC2 | |
| SCHEMBL6637138 | 0.89 | AGTR1 (1.00) | AGTR1ABCC3ABCC2 | |
| SCHEMBL6639612 | 0.89 | AGTR1 (1.00) | AGTR1ABCC3ABCC2 | |
| SCHEMBL6970475 | 0.89 | AGTR1 (0.87) | AGTR1ABCC3ABCC2 | |
| SCHEMBL683845 | 0.89 | AGTR1 (0.87) | AGTR1ABCC3ABCC2 | |
| SCHEMBL6963946 | 0.88 | AGTR1 (0.82) | AGTR1ABCC3ABCC2 | |
| SCHEMBL6963959 | 0.88 | AGTR1 (0.82) | AGTR1ABCC3ABCC2 | |
| SCHEMBL6957906 | 0.88 | AGTR1 (0.78) | AGTR1ABCC3ABCC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561977-B1 | USE OF ANGIOTENSIN II RECEPTOR ANTAGONISTS IN THE TREATMENT OF HEMORRAGIC STROKE | SMITHKLINE BEECHAM PLC (GB) | 2004-05-26 | — | — | EP | disclosed |
| EP-0724387-B1 | ANGIOTENSION II RECEPTOR ANTAGONISTS FOR THE TREATMENT OF CHRONIC ANTI-INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORP (US) | 2003-05-02 | — | — | EP | disclosed |
| EP-0565634-B1 | ANGIOTENSIN II RECEPTOR BLOCKING COMPOSITIONS | SMITHKLINE BEECHAM CORP (US) | 1999-03-17 | — | — | EP | disclosed |
| EP-0403159-A2 | Imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |