SCHEMBL6637288

SCHEMBL6637288

COC(=O)C(C)Oc1ncccc1Oc1cc(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)c(F)cc1Cl

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BCAT1 P54687 20/20 0.51
BCAT2 O15382 18/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6635723 0.92 BCAT1 (0.51) BCAT1BCAT2
SCHEMBL6638343 0.86 BCAT1 (0.53) BCAT1BCAT2
SCHEMBL16671007 0.85 BCAT1 (0.49) BCAT1BCAT2
SCHEMBL3952530 0.85 DHODH (0.36) BCAT1BCAT2
SCHEMBL6639151 0.84 BCAT1 (0.45) BCAT1BCAT2
SCHEMBL3237995 0.83 BCAT1 (0.53) BCAT1BCAT2
SCHEMBL29981219 0.83 BCAT1 (0.52) BCAT1BCAT2
SCHEMBL6639049 0.83 BCAT1 (0.52) BCAT1BCAT2
Methane SCHEMBL23535163 0.83 BCAT1 (0.53) BCAT1BCAT2
Methane SCHEMBL27842573 0.82 BCAT1 (0.51) BCAT1BCAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1122244-B1 Uracil compounds and their use SUMITOMO CHEMICAL CO (JP) 2004-09-29 EP claimed
US-6537948-B1 Have a wide range of herbicidal spectrum, and causes no phytotoxicity on crops SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-03-25 US claimed
EP-1122244-B1 Uracil compounds and their use SUMITOMO CHEMICAL CO (JP) 2004-09-29 EP disclosed