Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6633203 | 0.85 | RAB9A (0.40) | RAB9APOLBKMT2ALMNAMEN1 | |
| SCHEMBL6637614 | 0.79 | NTRK1 (0.42) | KMT2AMEN1 | |
| SCHEMBL6635325 | 0.78 | MAPT (0.45) | RAB9APOLBKMT2ALMNAMEN1 | |
| SCHEMBL6636649 | 0.77 | SMN1; SMN2 (0.45) | POLBKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL5221619 | 0.77 | POLB (0.49) | RAB9APOLBKMT2ALMNAMEN1 | |
| SCHEMBL6634717 | 0.77 | SMN1; SMN2 (0.44) | RAB9APOLBKMT2ALMNAMEN1 | |
| SCHEMBL5823724 | 0.77 | POLB (0.49) | RAB9APOLBKMT2ALMNAMEN1 | |
| SCHEMBL5338559 | 0.77 | RAB9A (0.49) | RAB9APOLBKMT2ALMNAMEN1 | |
| SCHEMBL5223131 | 0.77 | POLB (0.49) | RAB9APOLBKMT2ALMNAMEN1 | |
| SCHEMBL6691951 | 0.76 | RAB9A (0.42) | RAB9APOLBKMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487435-A1 | AZETIDINE DERIVATIVES AS CCR-3 RECEPTOR ANTAGONISTS | Novartis AG (CH) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003077907-A1 | AZETIDINE DERIVATIVES AS CCR-3 RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2003-09-25 | — | — | WO | disclosed |