Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.54 |
| ▸ | NPC1 | O15118 | 8/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 3/20 | 0.46 |
| ▸ | MMP9 | P14780 | 3/20 | 0.46 |
| ▸ | MMP8 | P22894 | 3/20 | 0.46 |
| ▸ | MMP13 | P45452 | 3/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5834557 | 0.82 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| Butane SCHEMBL6637575 | 0.82 | RAB9A (0.60) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL5834520 | 0.81 | HPSE (0.59) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL5834189 | 0.81 | HPSE (0.56) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL5835070 | 0.80 | HPSE (0.55) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL5835040 | 0.79 | HPSE (0.57) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL5834856 | 0.79 | HPSE (0.57) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL5834732 | 0.79 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL5834507 | 0.79 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL5834734 | 0.78 | RAB9A (0.66) | RAB9ANPC1SMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1483261-A1 | PHTHALIMIDE CARBOXYLIC ACID DERIVATIVES | Oxford GlycoSciences (UK) Ltd, Attn: Mary Gadsden (GB) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003074516-A1 | PHTHALIMIDE CARBOXYLIC ACID DERIVATIVES | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2003-09-12 | — | — | WO | disclosed |