Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 4/20 | 0.66 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.66 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.66 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.49 |
| ▸ | TFEB | P19484 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528919 | 0.85 | PTGER4 (0.68) | PTGER3PTGER4PTGER2PTGER1HTT | |
| SCHEMBL11685100 | 0.83 | PTGER1 (0.66) | PTGER3PTGER4PTGER2PTGER1HTT | |
| SCHEMBL1536282 | 0.83 | PTGER1 (0.66) | PTGER3PTGER4PTGER2PTGER1HTT | |
| SCHEMBL1536281 | 0.83 | PTGER1 (0.66) | PTGER3PTGER4PTGER2PTGER1HTT | |
| SCHEMBL11685091 | 0.83 | PTGER1 (0.66) | PTGER3PTGER4PTGER2PTGER1HTT | |
| SCHEMBL4064471 | 0.83 | PTGER1 (0.61) | PTGER3PTGER4PTGER2PTGER1HTT | |
| SCHEMBL8323200 | 0.82 | PTGER4 (0.94) | PTGER3PTGER4PTGER2PTGER1HTT | |
| SCHEMBL1356220 | 0.82 | PTGER1 (0.64) | PTGER3PTGER4PTGER2PTGER1HTT | |
| SCHEMBL14843147 | 0.82 | PTGER1 (0.64) | PTGER3PTGER4PTGER2PTGER1HTT | |
| SCHEMBL11685411 | 0.82 | PTGER4 (0.64) | PTGER3PTGER4PTGER2PTGER1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474419-A1 | AMIDES OF AMINOALKYL-SUBSTITUTED AZETIDINES, PYRROLIDINES, PIPERIDINES AND AZEPANES | NOVO NORDISK A/S (DK) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003064411-A1 | AMIDES OF AMINOALKYL-SUBSTITUTED AZETIDINES, PYRROLIDINES, PIPERIDINES AND AZEPANES | NOVO NORDISK A/S (DK) | 2003-08-07 | — | — | WO | disclosed |