Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 8/20 | 0.94 |
| ▸ | PTGER2 | P43116 | 8/20 | 0.94 |
| ▸ | PTGER3 | P43115 | 8/20 | 0.94 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.94 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.67 |
| ▸ | CDK1 | P06493 | 1/20 | 0.67 |
| ▸ | CDK4 | P11802 | 1/20 | 0.67 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.67 |
| ▸ | CCND1 | P24385 | 1/20 | 0.67 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.55 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.55 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323198 | 1.00 | PTGER4 (0.94) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL7968873 | 0.94 | PTGER4 (0.84) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL7968870 | 0.94 | PTGER4 (0.84) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL19511288 | 0.88 | PTGER4 (0.74) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL19511064 | 0.88 | PTGER4 (0.74) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL3114346 | 0.88 | PTGER4 (0.74) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL7798321 | 0.88 | PTGER4 (0.78) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL7798324 | 0.88 | PTGER4 (0.78) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL10352269 | 0.88 | PTGER4 (0.74) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL10352270 | 0.88 | PTGER4 (0.74) | PTGER4PTGER2PTGER3PTGER1CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101305321-A | Developable undercoating composition for thick photoresist layers | AZ ELECTRONIC MATERIALS USA (US) | 2008-11-12 | — | — | CN | claimed |
| EP-0733033-B1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LTD (GB) | 1999-12-22 | — | — | EP | disclosed |
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |
| EP-0733033-A1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LIMITED (GB) | 1996-09-25 | — | — | EP | disclosed |
| US-5374644-A | Insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-12-20 | — | — | US | disclosed |
| US-4851440-A | ASTHMA | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-07-25 | — | — | US | disclosed |