SCHEMBL6638015

SCHEMBL6638015

CCCCCC[Zr](Cl)(Cl)C1c2ccccc2-c2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.44
BCHE P06276 1/20 0.44
CHRM2 P08172 1/20 0.38
HTR1A P08908 1/20 0.38
ADRA2A P08913 1/20 0.38
CHRM1 P11229 1/20 0.38
DRD1 P21728 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
ADRA1A P35348 1/20 0.38
OPRM1 P35372 1/20 0.38
DRD3 P35462 1/20 0.38
SLC6A3 Q01959 1/20 0.38
HRH3 Q9Y5N1 1/20 0.38
HTR2A P28223 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7581041 0.76 ACHE (0.41) ACHEBCHECHRM2HTR1AADRA2A
SCHEMBL797705 0.75 ACHE (0.49) ACHEBCHECHRM2HTR1AADRA2A
SCHEMBL7195138 0.71 ACHE (0.41) ACHEBCHECHRM2HTR1AADRA2A
SCHEMBL30596219 0.71 ACHE (0.41) ACHEBCHECHRM2HTR1AADRA2A
SCHEMBL6060915 0.71 HTR2A (0.54) ACHEBCHEHTR2A
SCHEMBL6060774 0.71 HTR2A (0.54) ACHEBCHEHTR2A
SCHEMBL6060938 0.71 HTR2A (0.54) ACHEBCHEHTR2A
SCHEMBL6061696 0.71 HTR2A (0.54) ACHEBCHEHTR2A
SCHEMBL6061312 0.71 HTR2A (0.54) ACHEBCHEHTR2A
SCHEMBL407781 0.71 HTR2A (0.54) ACHEBCHEHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0908468-B1 Process for the (co)polymerisation of olefins SOLVAY (BE) 2004-05-26 EP disclosed
US-6555632-B1 Homo or copolymerization of alpha-olefin in presence of a catalyst system containing neutral halogenated metallocene catalyst, an organoaluminum compound, and an ionizing agent SOLVAY POLYOLEFINS EUROPE-BELGIUM (SOCIETE ANONYME) (BE) 2003-04-29 US disclosed
EP-0838476-B1 Solid precursor of a catalyst system for polymerization of olefins, process for its preparation and catalytic system containing said precursor and process for the polymerization of olefins using said catalyst system SOLVAY (BE) 2001-09-26 EP disclosed
US-6214948-B1 PLACING A SOLID PRECURSOR CONTAINING AT LEAST ONE NEUTRAL METALLOCENE DERIVED FROM TRANSITIONAL METAL AND AN IONIZING AGENT, IN CONTACT WITH ORGANOMETALLIC COMPOUND OF 1A, 2A, 2B, 3 AND 4 GROUP SOLVAY POLYOLEFINS EUROPE-BELGIUM (BE) 2001-04-10 US disclosed
US-6013595-A A CATALYTIC SOLID FOR THE (CO)POLYMERIZATION OF ETHYLENE, COMPRISING AT LEAST ONE INORGANIC SUPPORT, A TRANSITION METAL METALLOCENE, ATLEAST ONE IONIZATING AGENT AND A CHROMIUM COMPOUND SOLVAY (SOCIETE ANONYME) (BE) 2000-01-11 US disclosed
EP-0602716-B1 Catalyst system, process for its production and its use in (co)polymerization of olefins SOLVAY (BE) 1999-12-15 EP disclosed
EP-0733650-B1 Solid catalyst for (co)polymerizing ethylene, process for its preparation, catalyst system for the (co)polymerization of ethylene and process for the (co)polymerization of ethylene SOLVAY (BE) 1999-05-12 EP disclosed
EP-0908468-A2 Process for the (co)polymerisation of olefins SOLVAY POLYOLEFINS EUROPE - BELGIUM (Société Anonyme) (BE) 1999-04-14 EP disclosed
EP-0573120-B1 Process for producing a catalyst system, process for the (co)polymerization of olefins and (co)polymers of at least one olefin SOLVAY (BE) 1998-11-04 EP disclosed
US-5817725-A Process for the preparation of a catalytic system, process for the (CO) polymerization of olefins and (CO) polymers of at least one olefin SOLVAY POLYOLEFINS EUROPE-BELGIUM (SOCIETE ANONYME) (BE) 1998-10-06 US disclosed
EP-0613908-B1 Solid precursor of a catalytic system for polymerization of olefins, process for its preparation and catalytic system containing said precursor SOLVAY (BE) 1998-07-29 EP disclosed
US-5763349-A Solid precursor of a catalytic system for the polymerization of olefins, process for its preparation, catalytic system comprising this solid precursor and process for the polymerization of olefins in the presence of this catalytic system SOLVAY POLYOLEFINS EUROPE - BELGIUM (BE) 1998-06-09 US disclosed
EP-0838476-A1 Solid precursor of a catalyst system for polymerization of olefins, process for its preparation and catalytic system containing said precursor and process for the polymerization of olefins using said catalyst system SOLVAY POLYOLEFINS EUROPE - BELGIUM (Société Anonyme) (BE) 1998-04-29 EP disclosed
US-5719235-A Catalyst system, use of this catalyst system for the (co)polymerization of olefins, process for preparing this catalyst system and olefin (co)polymerization process SOLVAY (SOCIETE ANONYME) (BE) 1998-02-17 US disclosed
US-5612271-A Process for the prepration of a catalytic system, process for the (co)polymerization of olefins and (co)polymers of at least one olefin SOLVAY (SOCIETE ANONYME) (BE) 1997-03-18 US disclosed
EP-0733650-A1 Solid catalyst for (co)polymerizing ethylene, process for its preparation, catalyst system for the (co)polymerization of ethylene and process for the (co)polymerization of ethylene SOLVAY (Société Anonyme) (BE) 1996-09-25 EP disclosed
US-5496782-A Catalyst system, use of this catalyst system for the (co)polymerization of olefins, process for preparing this catalyst system and olefin (co) polymerization process Solvay (Socie/ te/ Anonyme) (BE) 1996-03-05 US disclosed
EP-0613908-A1 Solid precursor of a catalytic system for polymerization of olefins, process for its preparation and catalytic system containing said precursor SOLVAY (Société Anonyme) (BE) 1994-09-07 EP disclosed
EP-0602716-A1 Catalyst system, process for its production and its use in (co)polymerization of olefins SOLVAY (Société Anonyme) (BE) 1994-06-22 EP disclosed
EP-0573120-A1 Process for producing a catalyst system, process for the (co)polymerization of olefins and (co)polymers of at least one olefin SOLVAY (Société Anonyme) (BE) 1993-12-08 EP disclosed