Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 11/20 | 0.49 |
| ▸ | PPARA | Q07869 | 13/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4575449 | 1.00 | PPARD (0.49) | PPARDPPARAPPARGPKMKCNH2 | |
| SCHEMBL4574832 | 0.90 | FBP1 (0.40) | PPARDPPARAPPARGPKMKCNH2 | |
| SCHEMBL4575464 | 0.89 | PPARA (0.54) | PPARDPPARAPPARG | |
| SCHEMBL4576279 | 0.87 | PPARA (0.56) | PPARDPPARAPPARG | |
| SCHEMBL4575335 | 0.87 | PPARA (0.52) | PPARDPPARAPPARG | |
| SCHEMBL4575713 | 0.87 | PPARA (0.52) | PPARDPPARAPPARG | |
| SCHEMBL4575442 | 0.86 | PPARA (0.51) | PPARDPPARAPPARG | |
| SCHEMBL4575296 | 0.86 | PPARA (0.51) | PPARDPPARAPPARG | |
| SCHEMBL4575814 | 0.84 | PPARA (0.49) | PPARDPPARAPPARG | |
| SCHEMBL4575699 | 0.84 | PPARA (0.53) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480957-A1 | HPPARS ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003074495-A1 | HPPARS ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-09-12 | — | — | WO | disclosed |