Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6641211 | 0.90 | POLB (0.43) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL5095592 | 0.81 | MEN1 (0.78) | MEN1KMT2APOLBSMN1; SMN2ROCK2 | |
| SCHEMBL6639749 | 0.78 | ROCK2 (0.55) | MEN1KMT2APOLBROCK2ROCK1 | |
| SCHEMBL6636659 | 0.75 | KMT2A (0.60) | MEN1KMT2APOLBSMN1; SMN2ROCK2 | |
| SCHEMBL6994625 | 0.72 | POLB (0.53) | MEN1KMT2APOLBROCK2ROCK1 | |
| SCHEMBL7000901 | 0.72 | MAOB (0.72) | MEN1KMT2APOLBROCK2ROCK1 | |
| SCHEMBL6638216 | 0.71 | CCR3 (0.34) | ROCK2ALDH1A1 | |
| SCHEMBL5096125 | 0.70 | MEN1 (0.61) | MEN1KMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL13434069 | 0.70 | HPGD (0.69) | MEN1KMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL6999169 | 0.69 | MEN1 (0.60) | MEN1KMT2APOLBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984967-B1 | NAPHTHYRIDINE DERIVATIVES AND THEIR ANALOGUES INHIBITING CYTOMEGALOVIRUS | IAF BIOCHEM INT (CA) | 2004-02-25 | — | — | EP | claimed |
| EP-1037633-B1 | ANTIVIRAL COMPOUNDS | IAF BIOCHEM INT (CA) | 2003-09-10 | — | — | EP | claimed |