Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.78 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CTRC | Q99895 | 1/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.54 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.54 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | RBM39 | Q14498 | 1/20 | 0.52 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6638511 | 1.00 | MEN1 (0.78) | MEN1KMT2AGAAPOLBALDH1A1 | |
| SCHEMBL12530632 | 1.00 | MEN1 (0.78) | MEN1KMT2AGAAPOLBALDH1A1 | |
| SCHEMBL6638080 | 0.88 | KMT2A (0.75) | MEN1KMT2AGAAPOLBALDH1A1 | |
| SCHEMBL9911666 | 0.88 | KMT2A (0.75) | MEN1KMT2AGAAPOLBALDH1A1 | |
| SCHEMBL6638076 | 0.88 | KMT2A (0.75) | MEN1KMT2AGAAPOLBALDH1A1 | |
| SCHEMBL13908106 | 0.88 | KMT2A (1.00) | MEN1KMT2AGAAPOLBALDH1A1 | |
| SCHEMBL13908080 | 0.83 | KMT2A (0.71) | MEN1KMT2AGAAPOLBALDH1A1 | |
| SCHEMBL10027946 | 0.83 | MAPT (0.77) | MEN1KMT2AGAAPOLBALDH1A1 | |
| SCHEMBL6634160 | 0.83 | MEN1 (0.67) | MEN1KMT2AGAAPOLBALDH1A1 | |
| SCHEMBL6634162 | 0.83 | MEN1 (0.67) | MEN1KMT2AGAAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0909788-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | Bridgestone Corporation (JP) | 1999-04-21 | — | — | EP | claimed |
| EP-1420044-A2 | Rubber composition and pneumatic tire | Bridgestone Corporation (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6380288-B1 | LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS | BRIDGESTONE CORPORATION | 2002-04-30 | — | — | US | disclosed |
| EP-0909788-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | Bridgestone Corporation (JP) | 1999-04-21 | — | — | EP | disclosed |