Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.75 |
| ▸ | MEN1 | O00255 | 6/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | RBM39 | Q14498 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | RRM1 | P23921 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6638080 | 1.00 | KMT2A (0.75) | KMT2AMEN1ALDH1A1MAPTRBM39 | |
| SCHEMBL6638076 | 1.00 | KMT2A (0.75) | KMT2AMEN1ALDH1A1MAPTRBM39 | |
| SCHEMBL12530632 | 0.88 | MEN1 (0.78) | KMT2AMEN1ALDH1A1MAPTRBM39 | |
| SCHEMBL6638508 | 0.88 | MEN1 (0.78) | KMT2AMEN1ALDH1A1MAPTRBM39 | |
| SCHEMBL6638511 | 0.88 | MEN1 (0.78) | KMT2AMEN1ALDH1A1MAPTRBM39 | |
| SCHEMBL13908082 | 0.86 | ALDH1A1 (0.68) | KMT2AMEN1ALDH1A1MAPTRBM39 | |
| SCHEMBL13908106 | 0.86 | KMT2A (1.00) | KMT2AMEN1ALDH1A1MAPTRBM39 | |
| SCHEMBL13908088 | 0.86 | ALDH1A1 (0.81) | KMT2AMEN1ALDH1A1MAPTRBM39 | |
| SCHEMBL23752982 | 0.85 | KMT2A (0.64) | KMT2AMEN1ALDH1A1MAPTRBM39 | |
| SCHEMBL23752983 | 0.85 | KMT2A (0.64) | KMT2AMEN1ALDH1A1MAPTRBM39 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140364467-A1 | CHEMICAL INDUCERS OF NEUROGENESIS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-12-11 | — | — | US | disclosed |
| US-8778940-B2 | Chemical inducers of neurogenesis | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-07-15 | — | — | US | disclosed |
| US-20130143935-A1 | STEM CELL DIFFERENTIATING AGENTS AND USES THEREFOR | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-06-06 | — | — | US | disclosed |
| US-20130143885-A1 | CHEMICAL INDUCERS OF NEUROGENESIS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-06-06 | — | — | US | disclosed |
| US-8193225-B2 | Isoxazole amides, derivatives and methods of chemical induction of neurogenesis | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-06-05 | — | — | US | disclosed |
| US-20120029200-A1 | Stem Cell Differentiating Agents and Uses Therefor | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-02-02 | — | — | US | disclosed |
| US-7981935-B2 | Stem cell differentiating agents and uses therefor | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2011-07-19 | — | — | US | disclosed |
| WO-2009038879-A2 | STEM CELL DIFFERENTIATING AGENTS AND USES THEREFOR | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2009-03-26 | — | — | WO | disclosed |
| US-20090076103-A1 | STEM CELL DIFFERENTIATING AGENTS AND USES THEREFOR | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2009-03-19 | — | — | US | disclosed |
| US-20090036451-A1 | Chemical inducers of neurogenesis | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029200-A1 | Stem Cell Differentiating Agents and Uses Therefor | MYADM, MCL1, NOTCH4 | KMT2A 1982/4885MEN1 3309/4885ALDH1A1 28/4885 |
| US-20090076103-A1 | STEM CELL DIFFERENTIATING AGENTS AND USES THEREFOR | MYADM, MCL1, NOTCH4 | KMT2A 1982/4885MEN1 3309/4885ALDH1A1 28/4885 |
| US-20140364467-A1 | CHEMICAL INDUCERS OF NEUROGENESIS | DCX, NES, GAP43 | KMT2A 1862/4885MEN1 3223/4885ALDH1A1 415/4885 |
| US-20090036451-A1 | Chemical inducers of neurogenesis | DCX, NES, GAP43 | KMT2A 1862/4885MEN1 3223/4885ALDH1A1 415/4885 |
| US-20130143935-A1 | STEM CELL DIFFERENTIATING AGENTS AND USES THEREFOR | MYADM, MCL1, NOTCH4 | KMT2A 1982/4885MEN1 3309/4885ALDH1A1 28/4885 |
| US-20130143885-A1 | CHEMICAL INDUCERS OF NEUROGENESIS | DCX, NES, GAP43 | KMT2A 1862/4885MEN1 3223/4885ALDH1A1 415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.