SCHEMBL663852

SCHEMBL663852

CCCCCCCCC1(C)CCC(=O)O1

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.53
PRKCA P17252 12/20 0.44
CYP1A2 P05177 2/20 0.38
PTPN1 P18031 3/20 0.36
ACP1 P24666 2/20 0.36
CDC25B P30305 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15526485 1.00 SIRT2 (0.53) SIRT2PRKCACYP1A2PTPN1ACP1
SCHEMBL10186569 1.00 SIRT2 (0.53) SIRT2PRKCACYP1A2PTPN1ACP1
SCHEMBL10186571 1.00 SIRT2 (0.53) SIRT2PRKCACYP1A2PTPN1ACP1
SCHEMBL3659625 1.00 SIRT2 (0.53) SIRT2PRKCACYP1A2PTPN1ACP1
SCHEMBL112728 1.00 SIRT2 (0.53) SIRT2PRKCACYP1A2PTPN1ACP1
SCHEMBL3659630 0.98 SIRT2 (0.50) SIRT2PRKCACYP1A2PTPN1ACP1
SCHEMBL3658750 0.90 SIRT2 (0.61) SIRT2PRKCACYP1A2PTPN1ACP1
SCHEMBL3660815 0.90 SIRT2 (0.61) SIRT2PRKCACYP1A2PTPN1ACP1
SCHEMBL3658352 0.88 SIRT2 (0.59) SIRT2PRKCACYP1A2PTPN1ACP1
SCHEMBL3661073 0.85 SIRT2 (0.39) SIRT2PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9169625-A None JP disclosed
US-20260071137-A1 5,5-DISUBSTITUED TETRAHYDROFURAN-2-ONE AS FRAGRANCE COMPOUNDS SYMRISE AG (DE) 2026-03-12 US disclosed
EP-4074807-B1 COMPOSITIONS COMPRISING A FLUOROOLEFIN CHEMOURS CO FC LLC (US) 2025-07-09 EP disclosed
EP-4532645-A1 5,5-DISUBSTITUED TETRAHYDROFURAN-2-ONE AS FRAGRANCE COMPOUNDS Symrise AG (DE) 2025-04-09 EP disclosed
EP-3543310-B2 COMPOSITIONS COMPRISING HFC-1234YF AND HFC-32 CHEMOURS CO FC LLC (US) 2024-07-03 EP disclosed
EP-3299435-B1 METHOD OF PREPARING A COMPOSITION COMPRISING HFC-1234YF CHEMOURS CO FC LLC (US) 2024-06-26 EP disclosed
EP-2749623-B2 Method for replacing a high GWP refrigerant in a refrigeration, air-conditioning, or heat pump apparatus CHEMOURS CO FC LLC (US) 2024-02-21 EP disclosed
EP-3309233-B2 COMPOSITIONS COMPRISING HFC-1234YF AND HFC-152A CHEMOURS CO FC LLC (US) 2024-02-21 EP disclosed
WO-2023232241-A1 5,5-DISUBSTITUED TETRAHYDROFURAN-2-ONE AS FRAGRANCE COMPOUNDS SYMRISE AG (DE) 2023-12-07 WO disclosed
WO-2023232241-A1 5,5-DISUBSTITUED TETRAHYDROFURAN-2-ONE AS FRAGRANCE COMPOUNDS SYMRISE AG (DE) 2023-12-07 WO disclosed
US-20050151113-A1 Hydrofluorocarbon refrigerant compositions and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US disclosed
US-20050151110-A1 Fluoroether refrigerant compositions and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US disclosed
US-20050151112-A1 1,1,1,2,2,3,3,4,4-Nonafluoro-4-methoxybutane refrigerant compositions comprising hydrofluorocarbon, and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US disclosed
US-20050151111-A1 1,1,1,3,3-Pentafluorobutane refrigerant or heat transfer fluid compositions comprising hydrofluorocarbon and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US disclosed
US-20050145822-A1 Refrigerant compositions comprising UV fluorescent dye and solubilizing agent E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-07 US disclosed
US-20050127321-A1 Compositions containing lactone compatibilizers E. I. DU PONT DE NEMOURS AND COMPANY 2005-06-16 US disclosed
US-20050109978-A1 Refrigerant compositions comprising performance enhancing additives LECK THOMAS J (US) 2005-05-26 US disclosed
US-6841088-B2 Fluorocarbon, oxygenated and non-oxygenated lubricant, and compatibilizer composition, and method for replacing refrigeration composition in a refrigeration system E. I. DU PONT DE NEMOURS AND COMPANY (US) 2005-01-11 US disclosed
JP-H09169625-A BEAUTIFYING AND WHITENING AGENT AND PREPARATION FOR EXTERNAL USE FOR SKIN CONTAINING THE SAME KAO CORP 1997-06-30 JP disclosed
EP-0245772-B1 5,9-DIMETHYLHEPTADECANE PROCESS AND MEANS FOR FIGHTING THE MOUNTAIN-ASH BENTWING \"LEUCOPTERA SCITELLA\ BASF Aktiengesellschaft (DE) 1989-11-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071137-A1 5,5-DISUBSTITUED TETRAHYDROFURAN-2-ONE AS FRAGRANCE COMPOUNDS PRMT5, ACSL5, ELOVL5 SIRT2 564/4885PRKCA 3620/4885CYP1A2 162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.