Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.45 |
| ▸ | PPARA | Q07869 | 13/20 | 0.45 |
| ▸ | PPARD | Q03181 | 5/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4575331 | 0.89 | PPARA (0.46) | PPARGPPARAPPARDTRPM8 | |
| SCHEMBL4575588 | 0.89 | FBP1 (0.41) | PPARGPPARAPPARDTRPM8 | |
| SCHEMBL4574831 | 0.89 | PPARA (0.50) | PPARGPPARAPPARDTRPM8 | |
| SCHEMBL4575311 | 0.88 | PPARA (0.45) | PPARGPPARAPPARDTRPM8 | |
| SCHEMBL4575238 | 0.88 | PPARA (0.45) | PPARGPPARAPPARDTRPM8 | |
| SCHEMBL4575035 | 0.87 | PPARA (0.44) | PPARGPPARAPPARDTRPM8 | |
| SCHEMBL4575746 | 0.87 | PPARA (0.44) | PPARGPPARAPPARDTRPM8 | |
| SCHEMBL4575605 | 0.86 | PPARA (0.48) | PPARGPPARAPPARDTRPM8 | |
| SCHEMBL4575466 | 0.86 | PPARA (0.48) | PPARGPPARAPPARD | |
| SCHEMBL4575219 | 0.86 | PPARA (0.43) | PPARGPPARAPPARDTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480957-A1 | HPPARS ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003074495-A1 | HPPARS ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-09-12 | — | — | WO | disclosed |