SCHEMBL6639007

SCHEMBL6639007

O=C(/C=C/c1ccccc1)c1cccc(O)c1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HB P07237 5/20 0.79
MAOB P27338 4/20 0.70
CYP1B1 Q16678 3/20 0.70
MAPT P10636 2/20 0.70
PLIN1 O60240 1/20 0.70
LMNA P02545 1/20 0.70
BCHE P06276 1/20 0.70
TNFRSF1A P19438 1/20 0.70
ACHE P22303 1/20 0.70
RECQL P46063 1/20 0.70
PLIN5 Q00G26 1/20 0.70
ABHD5 Q8WTS1 1/20 0.70
USP2 O75604 1/20 0.68
CYP3A4 P08684 2/20 0.67
HSPD1 P10809 2/20 0.67
HSPE1 P61604 2/20 0.67
KMT2A Q03164 2/20 0.67
PKM P14618 1/20 0.67
NFKB1 P19838 1/20 0.67
RAB9A P51151 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5593205 1.00 P4HB (0.79) P4HBMAOBCYP1B1MAPTPLIN1
SCHEMBL2992884 0.91 P4HB (0.82) P4HBMAOBCYP1B1BCHEUSP2
SCHEMBL2992887 0.91 P4HB (0.82) P4HBMAOBCYP1B1BCHEUSP2
3-Hydroxy Chalcone SCHEMBL25235759 0.90 P4HB (0.74) P4HBMAOBCYP1B1MAPTPLIN1
3-Hydroxy Chalcone SCHEMBL1524799 0.90 P4HB (0.74) P4HBMAOBCYP1B1MAPTPLIN1
SCHEMBL27276844 0.90 P4HB (0.79) P4HBMAOBCYP1B1MAPTBCHE
3-Hydroxy Chalcone SCHEMBL1524800 0.90 P4HB (0.74) P4HBMAOBCYP1B1MAPTPLIN1
SCHEMBL7240218 0.89 P4HB (0.74) P4HBMAOBCYP1B1MAPTPLIN1
SCHEMBL13203405 0.89 CYP1B1 (0.81) P4HBMAOBCYP1B1MAPTPLIN1
SCHEMBL10715461 0.89 P4HB (0.64) P4HBMAOBCYP1B1MAPTPLIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-58099439-A None JP disclosed
WO-2026050367-A3 CHALCONE-RELATED HERBICIDES AND METHODS THEREOF COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2026-04-09 WO disclosed
WO-2026050367-A2 CHALCONE-RELATED HERBICIDES AND METHODS THEREOF COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2026-03-05 WO disclosed
CN-116375695-B Probe based on flavonoid compound and preparation method and application thereof 兰州大学 2024-11-15 CN disclosed
CN-116375695-A Probe based on flavonoid compound and preparation method and application thereof 兰州大学 2023-07-04 CN disclosed
CN-109503686-B Novel nucleoside phosphoramidate compounds and uses thereof 南京圣和药业股份有限公司 2022-03-11 CN disclosed
US-20210400997-A1 APPLICATIONS OF DIPHENYLPROPENONE COMPOUND IN PREPARING ANIMAL FEED ADDITIVE OR ANIMAL FEED PENG, Xianfeng (CN) 2021-12-30 US disclosed
CN-108314697-B Novel nucleoside phosphoramidate compounds and uses thereof 南京圣和药业股份有限公司 2021-05-07 CN disclosed
CN-108546277-B Novel nucleoside phosphoramidate compounds and uses thereof 南京圣和药业股份有限公司 2021-05-07 CN disclosed
US-9963480-B2 Nucleoside phosphoramidate compound and use thereof NANJING SANHOME PHARMACEUTICAL CO., LTD. (CN) 2018-05-08 US disclosed
EP-0919545-A2 Benzyloxy substituted aromatics and their use as fungicides ROHM AND HAAS COMPANY (US) 1999-06-02 EP disclosed
US-5886015-A APPLYING FUNGICIDE OR INSECTICIDE TO THE LOCUS OF THE SEED, PLANT OR SOIL ROHM AND HAAS COMPANY (US) 1999-03-23 US disclosed
US-5883125-A Benzyloxy substituted aromatics and their use as fungicides and insecticides ROHM AND HAAS COMPANY (US) 1999-03-16 US disclosed
EP-0811614-A1 Benzyloxy substituted aromatics and their use as fungicides and insecticides ROHM AND HAAS COMPANY (US) 1997-12-10 EP disclosed
EP-0811608-A1 Benzyloxy substituted aromatics containing an acrylyl moiety and their use as fungicides and insecticides ROHM AND HAAS COMPANY (US) 1997-12-10 EP disclosed
EP-0410359-B1 Substituted aminoalkoxy-benzene-derivatives HOFFMANN LA ROCHE (CH) 1994-01-26 EP disclosed
US-5214046-A Synergistic mixtures, inhibitors of sterol biosynthesis HOFFMANN-LA ROCHE INC. (US) 1993-05-25 US disclosed
US-5106878-A Synergistic effects with other fungicides HOFFMANN-LA ROCHE INC. (US) 1992-04-21 US disclosed
EP-0410359-A1 Substituted aminoalkoxy-benzene-derivatives F. HOFFMANN-LA ROCHE AG (CH) 1991-01-30 EP disclosed
JP-S5899439-A CHALCONE DERIVATIVE AND ITS PREPARATION AGENCY OF IND SCIENCE & TECHNOL 1983-06-13 JP disclosed