⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2304249 | 0.69 | — | — | |
| SCHEMBL414468 | 0.69 | — | — | |
| SCHEMBL9773297 | 0.69 | RAB9A (0.47) | — | |
| SCHEMBL13058962 | 0.65 | — | — | |
| SCHEMBL2465395 | 0.65 | — | — | |
| SCHEMBL9019359 | 0.65 | — | — | |
| SCHEMBL6184809 | 0.65 | — | — | |
| SCHEMBL11312058 | 0.65 | — | — | |
| SCHEMBL434410 | 0.65 | — | — | |
| SCHEMBL21737595 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140933-B1 | PROCESS FOR PREPARING N6-SUBSTITUTED DEAZA-ADENOSINE DERIVATIVES | AVENTIS PHARMA INC (US) | 2004-09-08 | — | — | EP | disclosed |
| US-6429315-B1 | CYCLIZATION BY REACTION WITH FORMIC ACID DERIVATIVE; DEBLOCKING, DEPROTECTION | AVENTIS PHARMACEUTICALS INC. | 2002-08-06 | — | — | US | disclosed |
| EP-1140933-A2 | PROCESS FOR PREPARING N6-SUBSTITUTED DEAZA-ADENOSINE DERIVATIVES | Aventis Pharmacueticals Products Inc. (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040584-A2 | PROCESS FOR PREPARING N6-SUBSTITUTED DEAZA-ADENOSINE DERIVATIVES | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 2000-07-13 | — | — | WO | disclosed |