Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 8/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27928028 | 0.79 | PRCP (0.65) | PRCPGAARECQLGID4MEN1 | |
| SCHEMBL29924130 | 0.76 | PRCP (0.61) | PRCPGAARECQLGID4MEN1 | |
| SCHEMBL6206852 | 0.76 | PRCP (0.61) | PRCPGAARECQLGID4MEN1 | |
| SCHEMBL23274866 | 0.76 | PRCP (0.61) | PRCPGAARECQLGID4MEN1 | |
| SCHEMBL4276972 | 0.76 | ADRA1A (0.40) | OPRM1NPSR1 | |
| SCHEMBL3140174 | 0.75 | PRCP (0.57) | PRCPGAARECQLGID4MEN1 | |
| SCHEMBL6028625 | 0.72 | PRCP (0.56) | PRCPGAARECQLGID4MEN1 | |
| SCHEMBL29924401 | 0.72 | PRCP (0.69) | PRCPGAARECQLGID4MEN1 | |
| SCHEMBL23274823 | 0.72 | PRCP (0.69) | PRCPGAARECQLGID4MEN1 | |
| SCHEMBL6084553 | 0.70 | PRCP (1.00) | PRCPGAARECQLGID4OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165557-B1 | ARYL AND HETEROARYL FUSED AMINOALKYL-IMIDAZOLE DERIVATIVES: SELECTIVE MODULATORS OF GABAa RECEPTORS | NEUROGEN CORP (US) | 2004-09-29 | — | — | EP | disclosed |