SCHEMBL6639561

SCHEMBL6639561

O=C=NC(c1ccccc1)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MIF P14174 3/20 0.34
ACP3 P15309 2/20 0.33
PARP1 P09874 1/20 0.32
CYP2D6 P10635 1/20 0.31
SRC P12931 1/20 0.31
POLB P06746 1/20 0.31
LMNA P02545 2/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2003043 0.80 MIF (0.38) MIFCYP2D6LMNA
SCHEMBL5694065 0.74 MIF (0.31) MIF
SCHEMBL2870631 0.72 MIF (0.38) MIFCYP2D6SRCLMNAMAPK1
SCHEMBL27678513 0.72 DPP4 (0.33) ACP3
SCHEMBL43325 0.72 SRC (0.42) MIFCYP2D6SRCLMNAMAPK1
SCHEMBL165792 0.72 MIF (0.40) MIFCYP2D6SRCLMNAMAPK1
SCHEMBL20146 0.72 MIF (0.40) MIFCYP2D6SRCLMNAMAPK1
SCHEMBL134389 0.72 MIF (0.40) MIFCYP2D6SRCLMNAMAPK1
SCHEMBL27749125 0.70 MIF (0.39) MIFCYP2D6SRCLMNAMAPK1
SCHEMBL1205494 0.70 MIF (0.39) MIFCYP2D6SRCLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122011331-A Preparation method of high-hydrophobicity corrosion-resistant fluorine-containing polyurea material 沈阳化工大学 2026-05-12 CN disclosed
WO-2021074279-A1 SPIRO-FUSED TRICYCLIC MAP4K1 INHIBITORS BAYER AKTIENGESELLSCHAFT (DE) 2021-04-22 WO disclosed
EP-1490340-A1 HETEROAROMATIC UREA DERIVATIVES AS VR-1 RECEPTOR MODULATORS FOR TREATING PAIN MERCK SHARP & DOHME LTD. (GB) 2004-12-29 EP disclosed
WO-2003080578-A1 HETEROAROMATIC UREA DERIVATIVES AS VR-1 RECEPTOR MODULATORS FOR TREATING PAIN MERCK SHARP & DOHME LIMITED (GB) 2003-10-02 WO disclosed
EP-0362001-B1 N-CYCLOALKYL BENZYLAMINES ALPHA,ALPHA DISUBSTITUTED, THE PROCESS FOR THEIR PREPARATION, THEIR USE AS DRUGS AND THEIR SYNTHESIS INTERMEDIATES JOUVEINAL S.A. (FR) 1993-03-10 EP disclosed
EP-0362001-A1 N-cycloalkyl benzylamines alpha,alpha disubstituted, the process for their preparation, their use as drugs and their synthesis intermediates JOUVEINAL S.A. (FR) 1990-04-04 EP disclosed