Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.65 |
| ▸ | RAB9A | P51151 | 9/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | PLK1 | P53350 | 1/20 | 0.57 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1563625 | 1.00 | NPC1 (0.65) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL1563626 | 1.00 | NPC1 (0.65) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL27178094 | 0.89 | NPC1 (0.60) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL27178018 | 0.89 | KMT2A (0.67) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL27178011 | 0.89 | KMT2A (0.67) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL27178104 | 0.89 | NPC1 (0.60) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL1563557 | 0.86 | RAB9A (0.56) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL1561989 | 0.86 | KMT2A (0.66) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL31622511 | 0.86 | KMT2A (0.66) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL27178102 | 0.85 | ATM (0.73) | NPC1RAB9AKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0909788-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | BRIDGESTONE CORP (JP) | 2004-12-01 | — | — | EP | disclosed |
| EP-1420044-A2 | Rubber composition and pneumatic tire | Bridgestone Corporation (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6380288-B1 | LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS | BRIDGESTONE CORPORATION | 2002-04-30 | — | — | US | disclosed |
| EP-0909788-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | Bridgestone Corporation (JP) | 1999-04-21 | — | — | EP | disclosed |