Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | USP7 | Q93009 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 3/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | GPR68 | Q15743 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6642648 | 0.82 | MEN1 (0.49) | SMN1; SMN2MEN1KMT2ACYP1A2MAPT | |
| SCHEMBL6643431 | 0.81 | MEN1 (0.48) | SMN1; SMN2MEN1KMT2ACYP1A2MAPT | |
| SCHEMBL6640744 | 0.80 | HRH4 (0.45) | SMN1; SMN2MEN1KMT2ACYP1A2MAPT | |
| SCHEMBL6642283 | 0.79 | MEN1 (0.54) | SMN1; SMN2MEN1KMT2ACYP1A2MAPT | |
| SCHEMBL6640763 | 0.78 | NPC1 (0.46) | SMN1; SMN2MEN1KMT2ACYP1A2MAPT | |
| SCHEMBL6641450 | 0.77 | MEN1 (0.52) | SMN1; SMN2MEN1KMT2ACYP1A2MAPT | |
| SCHEMBL6643416 | 0.76 | HRH4 (0.46) | SMN1; SMN2MEN1KMT2ACYP1A2MAPT | |
| SCHEMBL6639358 | 0.76 | CDK1 (0.54) | SMN1; SMN2MEN1KMT2ACYP1A2MAPT | |
| SCHEMBL6638090 | 0.76 | HSP90AA1 (0.49) | SMN1; SMN2MEN1KMT2ACYP1A2MAPT | |
| SCHEMBL6640942 | 0.75 | EGFR (0.45) | SMN1; SMN2MEN1KMT2ACYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412327-A2 | INHIBITORS OF PROTEIN KINASE FOR THE TREATMENT OF DISEASE | LG Biomedical Institute (US) | 2004-04-28 | — | — | EP | claimed |
| WO-2002096867-A2 | INHIBITORS OF PROTEIN KINASE FOR THE TREATMENT OF DISEASE | LG BIOMEDICAL INSTITUTE (US) | 2002-12-05 | — | — | WO | claimed |
| US-20030208067-A1 | Inhibitors of protein kinase for the treatment of disease | LG BIOMEDICAL INSTITUTE | 2003-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030208067-A1 | Inhibitors of protein kinase for the treatment of disease | MAP3K20, MAP3K1, MAP3K2 | SMN1; SMN2 2397/4885MEN1 2839/4885KMT2A 1417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.