Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | GBA1 | P04062 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6641589 | 0.81 | MAPK8 (0.39) | MAPK8POLBGBA1SMN1; SMN2MAPT | |
| SCHEMBL1484445 | 0.75 | POLB (0.40) | POLBGBA1MAPTTYMPKMT2A | |
| SCHEMBL5197709 | 0.70 | TYMP (0.38) | SMN1; SMN2MAPTTYMPKDM4EALDH1A1 | |
| SCHEMBL6085497 | 0.68 | PDE3B (0.41) | POLBMAPTTYMPKDM4EMAPK1 | |
| SCHEMBL6089500 | 0.65 | TPH1 (0.38) | SMN1; SMN2KMT2AMEN1LMNAKDM4E | |
| SCHEMBL17790717 | 0.64 | MAPK8 (0.47) | MAPK8POLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL1484498 | 0.64 | GBA1 (0.37) | POLBGBA1MAPTTYMPKMT2A | |
| SCHEMBL6086452 | 0.63 | PDE3B (0.38) | POLBSMN1; SMN2MAPTTYMPLMNA | |
| SCHEMBL6086721 | 0.63 | TYMP (0.37) | POLBSMN1; SMN2TYMPKDM4EALDH1A1 | |
| SCHEMBL14423060 | 0.60 | TYMP (0.47) | SMN1; SMN2TYMPKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159271-B1 | ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2004-08-25 | — | — | EP | disclosed |
| US-6713486-B1 | HIGH ACTIVITY AGAINST WILD-TYPE AND MUTANT HIV-1; LOW TOXICITY | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2004-03-30 | — | — | US | disclosed |