SCHEMBL664072

SCHEMBL664072

Nc1nc(N)nc(-c2ccccc2O)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 1.00
ADORA2A P29274 5/20 0.76
ADORA3 P0DMS8 2/20 0.76
ADORA2B P29275 2/20 0.76
ADORA1 P30542 2/20 0.76
ALDH1A1 P00352 1/20 0.76
ALOX15 P16050 1/20 0.76
TSHR P16473 1/20 0.76
NPC1 O15118 4/20 0.60
MAPT P10636 4/20 0.56
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
LMNA P02545 2/20 0.56
MAPK1 P28482 1/20 0.53
TDP1 Q9NUW8 2/20 0.53
CYP1A2 P05177 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
MAPK10 P53779 1/20 0.53
USP2 O75604 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30262243 1.00 SMN1; SMN2 (1.00) SMN1; SMN2ADORA2AADORA3ADORA2BADORA1
SCHEMBL8490844 0.96 SMN1; SMN2 (0.92) SMN1; SMN2ADORA2AADORA3ADORA2BADORA1
SCHEMBL27737323 0.87 ADORA2A (1.00) SMN1; SMN2ADORA2AADORA3ADORA2BADORA1
Toluene SCHEMBL27904873 0.85 SMN1; SMN2 (0.73) SMN1; SMN2ADORA2AADORA3ADORA2BADORA1
Chlorobenzene SCHEMBL27904895 0.85 SMN1; SMN2 (0.73) SMN1; SMN2ADORA2AADORA3ADORA2BADORA1
SCHEMBL195530 0.84 SMN1; SMN2 (0.71) SMN1; SMN2ADORA2AADORA3ADORA2BADORA1
SCHEMBL17046876 0.84 SMN1; SMN2 (0.71) SMN1; SMN2ADORA2AADORA3ADORA2BADORA1
SCHEMBL29502789 0.84 SMN1; SMN2 (0.71) SMN1; SMN2ADORA2AADORA3ADORA2BADORA1
SCHEMBL30468191 0.84 SMN1; SMN2 (0.71) SMN1; SMN2ADORA2AADORA3ADORA2BADORA1
SCHEMBL31683760 0.82 SMN1; SMN2 (0.69) SMN1; SMN2ADORA2AADORA3ADORA2BADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112638972-B Novel compositions and methods for producing alkoxylated triazine-arylhydroxy-aldehyde condensates 巴克莱特英国控股有限公司 2023-05-30 CN disclosed
CN-111108136-B Compositions for polyurethane applications 巴克莱特英国控股有限公司 2023-03-21 CN disclosed
EP-2606037-B1 NOVEL COMPOSITIONS AND METHODS TO PRODUCE TRIAZINE-ARYLHYDROXY-ALDEHYDE CONDENSATES WITH IMPROVED SOLUBILITY BAKELITE UK HOLDING LTD (GB) 2022-05-25 EP disclosed
EP-3833699-A1 NOVEL COMPOSITIONS AND METHODS TO PRODUCE ALKOXYLATED TRIAZINE-ARYLHYDROXY-ALDEHYDE CONDENSATES Hexion Research Belgium SA (BE) 2021-06-16 EP disclosed
US-11028219-B2 Compositions for polyurethane applications HEXION INC. (US) 2021-06-08 US disclosed
EP-3827040-A1 NOVEL COMPOSITIONS AND METHODS TO PRODUCE ALKOXYLATED TRIAZINE-ARYLHYDROXY-ALDEHYDE CONDENSATES Hexion Research Belgium SA (BE) 2021-06-02 EP disclosed
CN-112673036-A Novel compositions and methods for producing alkoxylated triazine-arylhydroxy-aldehyde condensates 瀚森公司 2021-04-16 CN disclosed
CN-112638972-A Novel compositions and methods for producing alkoxylated triazine-arylhydroxy-aldehyde condensates 瀚森公司 2021-04-09 CN disclosed
EP-3684830-A1 NOVEL COMPOSITIONS FOR POLYURETHANE APPLICATIONS Hexion Inc. (US) 2020-07-29 EP disclosed
EP-3684760-A2 NOVEL COMPOSITIONS AND METHODS TO PRODUCE ALKOXYLATED TRIAZINE-ARYLHYDROXY-ALDEHYDE CONDENSATES Hexion Research Belgium SA (BE) 2020-07-29 EP disclosed
US-20120046424-A1 NOVEL COMPOSITIONS AND METHODS TO PRODUCE TRIAZINE-ARYLHYDROXY-ALDEHYDE CONDENSATES WITH IMPROVED SOLUBILITY HEXION SPECIALTY CHEMICALS, INC. 2012-02-23 US disclosed
WO-2012024210-A1 NOVEL COMPOSITIONS AND METHODS TO PRODUCE TRIAZINE-ARYLHYDROXY-ALDEHYDE CONDENSATES WITH IMPROVED SOLUBILITY MOMENTIVE SPECIALTY CHEMICALS INC. (US) 2012-02-23 WO disclosed
EP-1193513-B1 Method of producing color filter DAINIPPON INK & CHEMICALS (JP) 2008-12-03 EP disclosed
EP-1174765-B1 Color filter and method for producing the same DAINIPPON INK & CHEMICALS (JP) 2006-05-03 EP disclosed
US-6929827-B2 Method of producing color filter DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-08-16 US disclosed
US-6524757-B2 Forming pattern using alkaline developers; photopolymerization DAINIPPON INK AND CHEMICALS, INC. (JP) 2003-02-25 US disclosed
US-20020081376-A1 Method of producing color filter DAINIPPON INK AND CHEMICALS, INC. (JP) 2002-06-27 US disclosed
EP-1193513-A2 Method of producing color filter DAINIPPON INK AND CHEMICALS, INC. (JP) 2002-04-03 EP disclosed
US-20020025481-A1 Color filter and method for producing the same DAINIPPON INK AND CHEMICALS, INC. (JP) 2002-02-28 US disclosed
EP-1174765-A1 Color filter and method for producing the same DAINIPPON INK AND CHEMICALS, INC. (JP) 2002-01-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11028219-B2 Compositions for polyurethane applications ALKBH3, ALKBH2, XRCC5 SMN1; SMN2 2722/4885ADORA2A 4687/4885ADORA3 4804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.