Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 15/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6633900 | 0.91 | F2 (0.50) | F2KMT2ALMNAGAAHTT | |
| SCHEMBL6636052 | 0.84 | F2 (0.43) | F2ALDH1A1KMT2ALMNAGAA | |
| SCHEMBL6635670 | 0.82 | F2 (0.74) | F2ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL8028428 | 0.82 | F2 (0.77) | F2 | |
| SCHEMBL6634705 | 0.82 | F2 (0.47) | F2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL6640819 | 0.81 | F2 (0.76) | F2KEAP1NFE2L2 | |
| SCHEMBL6637006 | 0.81 | F2 (0.75) | F2 | |
| SCHEMBL6637043 | 0.77 | F2 (0.44) | F2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL6638619 | 0.77 | HCRTR2 (0.43) | ALDH1A1KMT2ALMNAHTTKEAP1 | |
| Hydrochloric Acid SCHEMBL8026134 | 0.76 | F2 (0.64) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100795-B1 | DISUBSTITUTED BICYCLIC HETEROCYCLES HAVING, IN PARTICULAR, A THROMBIN INHIBITIVE EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-06-09 | — | — | EP | disclosed |
| US-6121308-A | INDOLE AND BENZIMIDAZOLE ANTITHROMBOTIC COMPOUNDS, SUCH AS 1-METHYL-2-(N-(4-AMIDINOPHENYL)-AMINOMETHYL)-5-(N-(HYDROXYCARBONYLMETHYL) -QUINOLINE-8-SULPHONYLAMINO)-INDOLE | BOEHRINGER INGELHEIM KG (DE) | 2000-09-19 | — | — | US | disclosed |