Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 3/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6633900 | 0.94 | F2 (0.50) | F2USP2MAPK1KMT2ALMNA | |
| SCHEMBL6635939 | 0.87 | HCRTR2 (0.43) | USP2MAPK1KMT2ALMNAHTT | |
| SCHEMBL6640824 | 0.84 | F2 (0.54) | F2KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL6635194 | 0.84 | F2 (0.39) | F2USP2MAPK1LMNAF10 | |
| SCHEMBL6636049 | 0.83 | F2 (0.57) | F2F10ITGB3ITGA2B | |
| SCHEMBL6638619 | 0.81 | HCRTR2 (0.43) | USP2MAPK1KMT2ALMNAHTT | |
| SCHEMBL6637043 | 0.79 | F2 (0.44) | F2F10HTTSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8029579 | 0.78 | F2 (0.70) | F2F10 | |
| SCHEMBL6634233 | 0.78 | F2 (0.62) | F2F10 | |
| SCHEMBL6633896 | 0.77 | F2 (0.65) | F2F10ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100795-B1 | DISUBSTITUTED BICYCLIC HETEROCYCLES HAVING, IN PARTICULAR, A THROMBIN INHIBITIVE EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-06-09 | — | — | EP | disclosed |