SCHEMBL6640832

SCHEMBL6640832

CCCCCCCCCCCCCCCCCC(=O)OC(C)(N)N

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DGKA P23743 1/20 0.53
▸ LMNA P02545 2/20 0.50
▸ PAM P19021 2/20 0.48
▸ MAPT P10636 2/20 0.47
▸ MAPK1 P28482 1/20 0.47
▸ CES2 O00748 3/20 0.46
▸ CES1 P23141 3/20 0.46
▸ TSHR P16473 5/20 0.46
▸ PPARG P37231 6/20 0.45
▸ PPARD Q03181 6/20 0.45
▸ PPARA Q07869 6/20 0.45
▸ HDAC11 Q96DB2 5/20 0.45
▸ GPR84 Q9NQS5 4/20 0.45
▸ ALDH1A1 P00352 2/20 0.45
▸ TLR2 O60603 2/20 0.45
▸ TDP1 Q9NUW8 2/20 0.45
▸ FABP4 P15090 2/20 0.45
▸ PTPN1 P18031 2/20 0.45
▸ SLC22A6 Q4U2R8 1/20 0.45
▸ SLC22A8 Q8TCC7 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29101740 0.88 DGKA (0.53) DGKALMNAPAMMAPTMAPK1
SCHEMBL11558967 0.88 DGKA (0.53) DGKALMNAPAMMAPTMAPK1
SCHEMBL1962326 0.88 DGKA (0.53) DGKALMNAPAMMAPTMAPK1
SCHEMBL1960961 0.88 DGKA (0.53) DGKALMNAPAMMAPTMAPK1
SCHEMBL21571495 0.88 DGKA (0.53) DGKALMNAPAMMAPTMAPK1
SCHEMBL4653622 0.88 DGKA (0.53) DGKALMNAPAMMAPTMAPK1
SCHEMBL11265103 0.86 DGKA (0.52) DGKALMNAPAMMAPTMAPK1
SCHEMBL3340147 0.86 DGKA (0.52) DGKALMNAPAMMAPTMAPK1
Hydrochloric Acid SCHEMBL20261931 0.86 DGKA (0.52) DGKALMNAPAMMAPTMAPK1
Hydrochloric Acid SCHEMBL29219017 0.86 DGKA (0.52) DGKALMNAPAMMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0953887-B1 Fuser member with silicone rubber and aluminium oxide layer XEROX CORP (US) 2004-05-19 — — EP disclosed
US-20020136903-A1 Theta solvents with functional siloxane adhesives improve adhesion to silicone rubber substrates XEROX CORPORATION 2002-09-26 — — US disclosed
US-6099673-A Method of coating fuser members XEROX CORPORATION (US) 2000-08-08 — — US disclosed
EP-0953887-A2 Fuser member with silicone rubber and aluminium oxide layer Xerox Corporation (US) 1999-11-03 — — EP disclosed
US-5918098-A Fuser member with silicone rubber and aluminum oxide layer XEROX CORPORATION (US) 1999-06-29 — — US disclosed
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