Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.67 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PAM | P19021 | 2/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.37 |
| ▸ | PPARD | Q03181 | 4/20 | 0.37 |
| ▸ | PPARA | Q07869 | 4/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1512983 | 0.95 | TSHR (0.75) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL35936 | 0.95 | TSHR (0.75) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL31389037 | 0.95 | TSHR (0.75) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL8845137 | 0.95 | TSHR (0.75) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL8844654 | 0.95 | TSHR (0.75) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL9420975 | 0.95 | TSHR (0.64) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL8846029 | 0.90 | TSHR (0.59) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL3392238 | 0.89 | TSHR (0.54) | TSHRTHRBTDP1ALDH1A1FNTA | |
| SCHEMBL6547122 | 0.88 | TSHR (0.56) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL3863278 | 0.87 | TSHR (0.55) | TSHRTHRBTDP1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120045485-A1 | SUSTAINED RELEASE DOSAGE FORM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2012-02-23 | — | — | US | disclosed |